Secretion of pro‐angiogenic extracellular vesicles during hypoxia is dependent on the autophagy‐related protein GABARAPL1

Abstract Tumour hypoxia is a hallmark of solid tumours and contributes to tumour progression, metastasis development and therapy resistance. In response to hypoxia, tumour cells secrete pro‐angiogenic factors to induce blood vessel formation and restore oxygen supply to hypoxic regions. Extracellula...

詳細記述

書誌詳細
主要な著者: Tom G. Keulers, Sten F. Libregts, Joel E.J. Beaumont, Kim G. Savelkouls, Johan Bussink, Hans Duimel, Ludwig Dubois, Marijke I. Zonneveld, Carmen López‐Iglesias, Karel Bezstarosti, Jeroen A. Demmers, Marc Vooijs, Marca Wauben, Kasper M.A. Rouschop
フォーマット: 論文
言語:English
出版事項: Wiley 2021-12-01
シリーズ:Journal of Extracellular Vesicles
主題:
オンライン・アクセス:https://doi.org/10.1002/jev2.12166