Multifunctional exosome-mimetics for targeted anti-glioblastoma therapy by manipulating protein corona

Multifunctional exosome-mimetics for targeted anti-glioblastoma therapy by manipulating protein corona

Abstract Targeted drug delivery to the glioblastoma (GBM) overcoming blood–brain barrier (BBB) has been challenging. Exosomes are promising vehicles for brain tumor drug delivery, but the production and purification hinder its application for nanomedicine. Besides, the formation of protein corona (P...

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Bibliographic Details
Main Authors: Jun-Yong Wu, Yong-Jiang Li, Jiemin Wang, Xiong-Bin Hu, Si Huang, Shilin Luo, Da-Xiong Xiang
Format: Article
Language:English
Published: BMC 2021-12-01
Series:Journal of Nanobiotechnology
Subjects:
Blood–brain barrier
Exosomes
Exosome-mimetics
Drug delivery
Glioblastoma
Online Access:https://doi.org/10.1186/s12951-021-01153-3

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