Neuromedin U secreted by colorectal cancer cells promotes a tumour-supporting microenvironment

Neuromedin U secreted by colorectal cancer cells promotes a tumour-supporting microenvironment

Abstract Background Neuromedin U (NMU) was identified as one of the hub genes closely related to colorectal cancer (CRC) progression and was recently shown to be a motility inducer in CRC cells. Its autocrine signalling through specific receptors increases cancer cell migration and invasiveness. Bec...

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Bibliographic Details
Main Authors: Patrycja Przygodzka, Kamila Soboska, Ewelina Sochacka, Marcin Pacholczyk, Marcin Braun, Hassan Kassassir, Izabela Papiewska-Pająk, Michal Kielbik, Joanna Boncela
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Cell Communication and Signaling
Subjects:
Colorectal cancer
Neuromedin U
NMU receptors
Macrophages
Endothelial cells
Online Access:https://doi.org/10.1186/s12964-022-01003-1

Internet

https://doi.org/10.1186/s12964-022-01003-1

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