Psychometric assessment of patients with central serous chorioretinopathy and correlation with disease stage and progression: a case control study
Abstract Background Central serous chorioretinopathy (CSC) has frequently been associated with increased stress levels as well as an increased prevalence of other psychiatric conditions. This study used standardized psychometric scores to assess stress, depression and anxiety levels of CSC patients...
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| Format: | Article |
| Language: | English |
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BMC
2024-02-01
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| Series: | BMC Ophthalmology |
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| Online Access: | https://doi.org/10.1186/s12886-024-03356-2 |
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| author | Hinrich J. Hufnagel Claas Lahmann Hansjürgen Agostini Clemens Lange Laurenz J. B. Pauleikhoff on behalf of the Retina.net CCS study group |
| author_facet | Hinrich J. Hufnagel Claas Lahmann Hansjürgen Agostini Clemens Lange Laurenz J. B. Pauleikhoff on behalf of the Retina.net CCS study group |
| author_sort | Hinrich J. Hufnagel |
| collection | DOAJ |
| description | Abstract Background Central serous chorioretinopathy (CSC) has frequently been associated with increased stress levels as well as an increased prevalence of other psychiatric conditions. This study used standardized psychometric scores to assess stress, depression and anxiety levels of CSC patients and compared them to controls without retinal disease (“healthy”) and with branch retinal vein occlusion (BRVO). Methods Monocentric, longitudinal case control study on consecutive CSC patients seen at a tertiary referral center. Controls without retinal disease were recruited from the oculoplastics clinic and those with BRVO from the medical retina clinic. Patients completed pseudonymized tests measuring stress levels (PHQ-stress), depression (PHQ-9) and anxiety (GAD-7) at baseline and at 3- and 6-months follow-up. Higher scores indicated higher trait levels. Results 65 CSC patients, 19 healthy controls and 19 BRVO patients were included in this study. CSC patients showed significantly higher stress levels at baseline compared to controls (p = 0.009), but not compared to BRVO patients (p = 1.00). At 3- and 6-months follow-up, no significant difference between groups was observed anymore. Acute CSC patients showed higher scores than those with chronic CSC, which also subsided over time. Depression and anxiety scores did not differ between groups at any timepoint. Conclusions Patients with CSC do not show higher initial stress levels than patients with BRVO, while anxiety and depression levels did not differ from controls. Stress may thus rather represent a consequence of the onset of visual deterioration observed in CSC or other ocular diseases. |
| first_indexed | 2024-03-07T15:14:20Z |
| format | Article |
| id | doaj.art-af77bf2425df43bc824eb037ffe39858 |
| institution | Directory Open Access Journal |
| issn | 1471-2415 |
| language | English |
| last_indexed | 2024-03-07T15:14:20Z |
| publishDate | 2024-02-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Ophthalmology |
| spelling | doaj.art-af77bf2425df43bc824eb037ffe398582024-03-05T18:02:40ZengBMCBMC Ophthalmology1471-24152024-02-012411810.1186/s12886-024-03356-2Psychometric assessment of patients with central serous chorioretinopathy and correlation with disease stage and progression: a case control studyHinrich J. Hufnagel0Claas Lahmann1Hansjürgen Agostini2Clemens Lange3Laurenz J. B. Pauleikhoff4on behalf of the Retina.net CCS study groupEye Center, Medical Center – University of Freiburg, Faculty of Medicine, University of FreiburgDepartment of Psychosomatic Medicine and Psychotherapy, Medical Center – University of Freiburg, Faculty of Medicine, University of FreiburgEye Center, Medical Center – University of Freiburg, Faculty of Medicine, University of FreiburgEye Center, Medical Center – University of Freiburg, Faculty of Medicine, University of FreiburgEye Center, Medical Center – University of Freiburg, Faculty of Medicine, University of FreiburgAbstract Background Central serous chorioretinopathy (CSC) has frequently been associated with increased stress levels as well as an increased prevalence of other psychiatric conditions. This study used standardized psychometric scores to assess stress, depression and anxiety levels of CSC patients and compared them to controls without retinal disease (“healthy”) and with branch retinal vein occlusion (BRVO). Methods Monocentric, longitudinal case control study on consecutive CSC patients seen at a tertiary referral center. Controls without retinal disease were recruited from the oculoplastics clinic and those with BRVO from the medical retina clinic. Patients completed pseudonymized tests measuring stress levels (PHQ-stress), depression (PHQ-9) and anxiety (GAD-7) at baseline and at 3- and 6-months follow-up. Higher scores indicated higher trait levels. Results 65 CSC patients, 19 healthy controls and 19 BRVO patients were included in this study. CSC patients showed significantly higher stress levels at baseline compared to controls (p = 0.009), but not compared to BRVO patients (p = 1.00). At 3- and 6-months follow-up, no significant difference between groups was observed anymore. Acute CSC patients showed higher scores than those with chronic CSC, which also subsided over time. Depression and anxiety scores did not differ between groups at any timepoint. Conclusions Patients with CSC do not show higher initial stress levels than patients with BRVO, while anxiety and depression levels did not differ from controls. Stress may thus rather represent a consequence of the onset of visual deterioration observed in CSC or other ocular diseases.https://doi.org/10.1186/s12886-024-03356-2Central serous chorioretinopathyDepressionAnxietyStressRetinal vein occlusion |
| spellingShingle | Hinrich J. Hufnagel Claas Lahmann Hansjürgen Agostini Clemens Lange Laurenz J. B. Pauleikhoff on behalf of the Retina.net CCS study group Psychometric assessment of patients with central serous chorioretinopathy and correlation with disease stage and progression: a case control study BMC Ophthalmology Central serous chorioretinopathy Depression Anxiety Stress Retinal vein occlusion |
| title | Psychometric assessment of patients with central serous chorioretinopathy and correlation with disease stage and progression: a case control study |
| title_full | Psychometric assessment of patients with central serous chorioretinopathy and correlation with disease stage and progression: a case control study |
| title_fullStr | Psychometric assessment of patients with central serous chorioretinopathy and correlation with disease stage and progression: a case control study |
| title_full_unstemmed | Psychometric assessment of patients with central serous chorioretinopathy and correlation with disease stage and progression: a case control study |
| title_short | Psychometric assessment of patients with central serous chorioretinopathy and correlation with disease stage and progression: a case control study |
| title_sort | psychometric assessment of patients with central serous chorioretinopathy and correlation with disease stage and progression a case control study |
| topic | Central serous chorioretinopathy Depression Anxiety Stress Retinal vein occlusion |
| url | https://doi.org/10.1186/s12886-024-03356-2 |
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