HIF-1α in Osteoarthritis: From Pathogenesis to Therapeutic Implications

HIF-1α in Osteoarthritis: From Pathogenesis to Therapeutic Implications

Osteoarthritis is a common age-related joint degenerative disease. Pain, swelling, brief morning stiffness, and functional limitations are its main characteristics. There are still no well-established strategies to cure osteoarthritis. Therefore, better clarification of mechanisms associated with th...

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Bibliographic Details
Main Authors:	Chu-Yang Zeng, Xi-Feng Wang, Fu-Zhou Hua
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-07-01
Series:	Frontiers in Pharmacology
Subjects:	osteoarthritis HIF-1α hypoxia chondrocytes glycolysis mitophagy
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2022.927126/full

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