Unexpected scaffold rearrangement product of pirenzepine found in commercial samples

Abstract Pharmacovigilance aims at a better understanding of the molecular events triggered by medications to prevent adverse effects, which despite significant advances in our analytical repertoire plague the use of drugs until today. In this study, we find that clinically prescribed and commercial...

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Main Authors: Marius Ozenil, Lukas Skos, Alexander Roller, Natalie Gajic, Wolfgang Holzer, Helmut Spreitzer, Sonja Platzer-Ozenil, Chrysoula Vraka, Marcus Hacker, Wolfgang Wadsak, Verena Pichler
פורמט: Article
שפה:English
יצא לאור: Nature Portfolio 2021-12-01
סדרה:Scientific Reports
גישה מקוונת:https://doi.org/10.1038/s41598-021-02732-y