Unexpected scaffold rearrangement product of pirenzepine found in commercial samples
Abstract Pharmacovigilance aims at a better understanding of the molecular events triggered by medications to prevent adverse effects, which despite significant advances in our analytical repertoire plague the use of drugs until today. In this study, we find that clinically prescribed and commercial...
Главные авторы: | Marius Ozenil, Lukas Skos, Alexander Roller, Natalie Gajic, Wolfgang Holzer, Helmut Spreitzer, Sonja Platzer-Ozenil, Chrysoula Vraka, Marcus Hacker, Wolfgang Wadsak, Verena Pichler |
---|---|
Формат: | Статья |
Язык: | English |
Опубликовано: |
Nature Portfolio
2021-12-01
|
Серии: | Scientific Reports |
Online-ссылка: | https://doi.org/10.1038/s41598-021-02732-y |
Схожие документы
-
Synthesis, Biological, and Computational Evaluation of Antagonistic, Chiral Hydrobenzoin Esters of Arecaidine Targeting mAChR M1
по: Marius Ozenil, и др.
Опубликовано: (2020-11-01) -
Synthesis, Biological Evaluation, and Docking Studies of Antagonistic Hydroxylated Arecaidine Esters Targeting mAChRs
по: Jonas Kilian, и др.
Опубликовано: (2022-05-01) -
Update on PET Tracer Development for Muscarinic Acetylcholine Receptors
по: Marius Ozenil, и др.
Опубликовано: (2021-06-01) -
Design, Synthesis, and Biological Evaluation of 4,4’-Difluorobenzhydrol Carbamates as Selective M<sub>1</sub> Antagonists
по: Jonas Kilian, и др.
Опубликовано: (2022-02-01) -
On the Road towards Small-Molecule Programmed Cell Death 1 Ligand 1 Positron Emission Tomography Tracers: A Ligand-Based Drug Design Approach
по: Karsten Bamminger, и др.
Опубликовано: (2023-07-01)