Comparison of Oral and Vaginal Route of Misoprostol for Induction of Labour at Term
Background: To compare the Induction – Delivery interval between Oral and Vaginal route of Misoprostol at term. Methods: In this comparative study , one hundred women at term with indications for induction of labour and Bishop score < 5, having no other obstetric and maternal contraindications fo...
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| Format: | Article |
| Language: | English |
| Published: |
Rawalpindi Medical University
2012-06-01
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| Series: | Journal of Rawalpindi Medical College |
| Subjects: | |
| Online Access: | https://www.journalrmc.com/index.php/JRMC/article/view/631 |
| Summary: | Background: To compare the Induction – Delivery
interval between Oral and Vaginal route of Misoprostol at
term.
Methods: In this comparative study , one hundred
women at term with indications for induction of labour
and Bishop score < 5, having no other obstetric and
maternal contraindications for induction of labour were
randomly assigned to receive Misoprostol 50 g orally and
50 g vaginally every 6 hours for 24 hours for a total of
four doses. Repeated doses were given until Bishop score
> 8 was achieved or spontaneous rupture of membranes
occurred. Student’s t test was applied to compare
induction delivery interval between oral and vaginal
groups and statistical significance was assigned to P- value
< 0.05.
Results: The median induction to delivery interval time
was significantly shorter with vaginal Misoprostol (11.0 h),
compared with oral Misoprostol (14.1 h, p= 0.036). There
was no difference between two routes of administration
with respect to rates of hyperstimulation or neonatal
asphyxia.
Conclusions: Compared with oral Misoprostol,
vaginal Misoprostol for induction of labour at term results
in a shorter induction to delivery interval time. There were
more caesarean section in the vaginal Misoprostol group. |
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| ISSN: | 1683-3562 1683-3570 |