Effects of intravenous lignocaine on anaesthetic parameters in cattle under dexmedetomidine-butorphanol-ketaminemidazolam- isofluraneanaesthesia

The present study was conducted for clinical evaluation of a multimodal anaesthetic protocol using butorphanol-dexmedetomidine-midazolam-ketamine-isoflurane and lignocaine continuous rate infusion (CRI) in six cross-bred female cattle. Preanaesthetics used were butorphanol and dexmedetomidine which...

Full description

Bibliographic Details
Main Authors: V. Jayakrishnan, S. Sudheesh Nair, Reji Varghese, Soumya Ramankutty, Preethy John, K.D. John Martin
Format: Article
Language:English
Published: Director of Academics and Research, Kerala Veterinary and Animal Sciences University 2023-03-01
Series:Journal of Veterinary and Animal Sciences
Subjects:
Online Access:https://jvas.in/public_html/upload/article_file/article_file_rsf6hv.pdf?t=rsf6hv
_version_ 1797847924963540992
author V. Jayakrishnan
S. Sudheesh Nair
Reji Varghese
Soumya Ramankutty
Preethy John
K.D. John Martin
author_facet V. Jayakrishnan
S. Sudheesh Nair
Reji Varghese
Soumya Ramankutty
Preethy John
K.D. John Martin
author_sort V. Jayakrishnan
collection DOAJ
description The present study was conducted for clinical evaluation of a multimodal anaesthetic protocol using butorphanol-dexmedetomidine-midazolam-ketamine-isoflurane and lignocaine continuous rate infusion (CRI) in six cross-bred female cattle. Preanaesthetics used were butorphanol and dexmedetomidine which were administered intravenously at dose rates of 0.05 mg/kg and 1 μg/ kg body weight, respectively. Ketamine and midazolam were intravenously administered at dose rates of 4.0 and 0.2 mg/kg body weight respectively, to induce anaesthesia. Isoflurane was used to maintain anaesthesia after endotracheal intubation, at a concentration of 1.05 ± 0.97 per cent concentration in 100 per cent oxygen using a large animal anaesthesia machine. Simultaneously, intravenous lignocaine was administered at a bolus dose of 2 mg/kg body weight followed by a CRI of 3 mg/kg body weight/hour using a volumetric infusion pump. Isoflurane sparing effect of intravenous lignocaine reduced the required concentration of isoflurane for maintenance. The third plane of surgical anaesthesia was maintained and various surgical procedures were done. Recovery was smooth. Other than the mild regurgitation of ruminal fluid in an animal, no anaesthetic complications were noticed.
first_indexed 2024-04-09T18:20:15Z
format Article
id doaj.art-af8be0d8798c498da220e035c62a911e
institution Directory Open Access Journal
issn 0971-0701
2582-0605
language English
last_indexed 2024-04-09T18:20:15Z
publishDate 2023-03-01
publisher Director of Academics and Research, Kerala Veterinary and Animal Sciences University
record_format Article
series Journal of Veterinary and Animal Sciences
spelling doaj.art-af8be0d8798c498da220e035c62a911e2023-04-12T09:46:12ZengDirector of Academics and Research, Kerala Veterinary and Animal Sciences UniversityJournal of Veterinary and Animal Sciences0971-07012582-06052023-03-0154119820310.51966/jvas.2023.54.1.198-203Effects of intravenous lignocaine on anaesthetic parameters in cattle under dexmedetomidine-butorphanol-ketaminemidazolam- isofluraneanaesthesiaV. Jayakrishnan0S. Sudheesh Nair1https://orcid.org/0000-0002-1209-8741Reji Varghese2Soumya Ramankutty3https://orcid.org/0000-0001-8861-3001Preethy John4K.D. John Martin5MVSc. scholar, Department of Veterinary Surgery and Radiology, College of Veterinary and Animal Sciences, Mannuthy, Thrissur-680651, Kerala Veterinary and Animal Sciences University, Pookode, Kerala, India.Assistant Professor, Department of Veterinary Surgery and Radiology, College of Veterinary and Animal Sciences, Mannuthy, Thrissur-680651, Kerala Veterinary and Animal Sciences University, Pookode, Kerala, India.Assistant Professor, Teaching Veterinary Clinical Complex, College of Veterinary and Animal Sciences, Mannuthy, Thrissur-680651, Kerala Veterinary and Animal Sciences University, Pookode, Kerala, India.Assistant Professor, Department of Veterinary Surgery and Radiology, College of Veterinary and Animal Sciences, Mannuthy, Thrissur-680651, Kerala Veterinary and Animal Sciences University, Pookode, Kerala, India.Assistant Professor, Department of Veterinary Pharmacology and Toxicology, College of Veterinary and Animal Sciences, Mannuthy, Thrissur-680651, Kerala Veterinary and Animal Sciences University, Pookode, Kerala, India.Professor and Head, Department of Veterinary Surgery and Radiology, College of Veterinary and Animal Sciences, Mannuthy, Thrissur-680651, Kerala Veterinary and Animal Sciences University, Pookode, Kerala, India.The present study was conducted for clinical evaluation of a multimodal anaesthetic protocol using butorphanol-dexmedetomidine-midazolam-ketamine-isoflurane and lignocaine continuous rate infusion (CRI) in six cross-bred female cattle. Preanaesthetics used were butorphanol and dexmedetomidine which were administered intravenously at dose rates of 0.05 mg/kg and 1 μg/ kg body weight, respectively. Ketamine and midazolam were intravenously administered at dose rates of 4.0 and 0.2 mg/kg body weight respectively, to induce anaesthesia. Isoflurane was used to maintain anaesthesia after endotracheal intubation, at a concentration of 1.05 ± 0.97 per cent concentration in 100 per cent oxygen using a large animal anaesthesia machine. Simultaneously, intravenous lignocaine was administered at a bolus dose of 2 mg/kg body weight followed by a CRI of 3 mg/kg body weight/hour using a volumetric infusion pump. Isoflurane sparing effect of intravenous lignocaine reduced the required concentration of isoflurane for maintenance. The third plane of surgical anaesthesia was maintained and various surgical procedures were done. Recovery was smooth. Other than the mild regurgitation of ruminal fluid in an animal, no anaesthetic complications were noticed.https://jvas.in/public_html/upload/article_file/article_file_rsf6hv.pdf?t=rsf6hvcattlelignocaineisoflurane sparing
spellingShingle V. Jayakrishnan
S. Sudheesh Nair
Reji Varghese
Soumya Ramankutty
Preethy John
K.D. John Martin
Effects of intravenous lignocaine on anaesthetic parameters in cattle under dexmedetomidine-butorphanol-ketaminemidazolam- isofluraneanaesthesia
Journal of Veterinary and Animal Sciences
cattle
lignocaine
isoflurane sparing
title Effects of intravenous lignocaine on anaesthetic parameters in cattle under dexmedetomidine-butorphanol-ketaminemidazolam- isofluraneanaesthesia
title_full Effects of intravenous lignocaine on anaesthetic parameters in cattle under dexmedetomidine-butorphanol-ketaminemidazolam- isofluraneanaesthesia
title_fullStr Effects of intravenous lignocaine on anaesthetic parameters in cattle under dexmedetomidine-butorphanol-ketaminemidazolam- isofluraneanaesthesia
title_full_unstemmed Effects of intravenous lignocaine on anaesthetic parameters in cattle under dexmedetomidine-butorphanol-ketaminemidazolam- isofluraneanaesthesia
title_short Effects of intravenous lignocaine on anaesthetic parameters in cattle under dexmedetomidine-butorphanol-ketaminemidazolam- isofluraneanaesthesia
title_sort effects of intravenous lignocaine on anaesthetic parameters in cattle under dexmedetomidine butorphanol ketaminemidazolam isofluraneanaesthesia
topic cattle
lignocaine
isoflurane sparing
url https://jvas.in/public_html/upload/article_file/article_file_rsf6hv.pdf?t=rsf6hv
work_keys_str_mv AT vjayakrishnan effectsofintravenouslignocaineonanaestheticparametersincattleunderdexmedetomidinebutorphanolketaminemidazolamisofluraneanaesthesia
AT ssudheeshnair effectsofintravenouslignocaineonanaestheticparametersincattleunderdexmedetomidinebutorphanolketaminemidazolamisofluraneanaesthesia
AT rejivarghese effectsofintravenouslignocaineonanaestheticparametersincattleunderdexmedetomidinebutorphanolketaminemidazolamisofluraneanaesthesia
AT soumyaramankutty effectsofintravenouslignocaineonanaestheticparametersincattleunderdexmedetomidinebutorphanolketaminemidazolamisofluraneanaesthesia
AT preethyjohn effectsofintravenouslignocaineonanaestheticparametersincattleunderdexmedetomidinebutorphanolketaminemidazolamisofluraneanaesthesia
AT kdjohnmartin effectsofintravenouslignocaineonanaestheticparametersincattleunderdexmedetomidinebutorphanolketaminemidazolamisofluraneanaesthesia