Immunomodulatory and anti-inflammatory therapeutic potential of gingerols and their nanoformulations

Immunomodulatory and anti-inflammatory therapeutic potential of gingerols and their nanoformulations

Ginger (Zingiber officinale Roscoe), a member of the Zingiberaceae family, is one of the most popular spices worldwide, known since ancient times, and used both as a spice and a medicinal plant. The phenolic compounds found in ginger are predominantly gingerols, shogaols, and paradols. Gingerols are...

Full description

Bibliographic Details
Main Authors:	Çiğdem Yücel, Gökçe Şeker Karatoprak, Özlem Bahadır Açıkara, Esra Küpeli Akkol, Timur Hakan Barak, Eduardo Sobarzo-Sánchez, Michael Aschner, Samira Shirooie
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-09-01
Series:	Frontiers in Pharmacology
Subjects:	cytokine immunomodulatory ginger gingerol Zingiber officinale
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2022.902551/full

Similar Items

[6]-Gingerol: A narrative review of its beneficial effect on human health
by: Nantaporn Promdam, et al.
Published: (2022-10-01)

Ginger and Testosterone
by: Saleem Ali Banihani
Published: (2018-10-01)

Nine New Gingerols from the Rhizoma of Zingiber officinale and Their Cytotoxic Activities
by: Zezhi Li, et al.
Published: (2018-02-01)

Gingerol, a Natural Antioxidant, Attenuates Hyperglycemia and Downstream Complications
by: Khalid Saad Alharbi, et al.
Published: (2022-12-01)

Land Characteristics Impact Productivity and Quality of Ginger (Zingiber officinale Rosc) in Java, Indonesia
by: Nur Azizah, et al.
Published: (2019-10-01)

The Effect of Ginger and Its Sub-Components on Pain
by: Suyong Kim, et al.
Published: (2022-09-01)

6-Gingerol, a Major Constituent of <i>Zingiber officinale</i> Rhizoma, Exerts Anticonvulsant Activity in the Pentylenetetrazole-Induced Seizure Model in Larval Zebrafish
by: Kinga Gawel, et al.
Published: (2021-07-01)

Gingerol supplementation does not change glucose tolerance, lipid profile and does not prevent weight gain in C57BL/6 mice fed a high-fat diet
by: Aline Jose Coelho Moreira Zordan, et al.
Published: (2020-08-01)

Oxidative Stress and Marine Carotenoids: Application by Using Nanoformulations
by: Yasin Genç, et al.
Published: (2020-08-01)

Effect of [6]-gingerol on viral neuraminidase and hemagglutinin-specific T cell immunity in severe influenza
by: Avijit Dutta, et al.
Published: (2023-02-01)

Ginger from Farmyard to Town: Nutritional and Pharmacological Applications
by: Jeremiah Oshiomame Unuofin, et al.
Published: (2021-11-01)

Pengaruh Penggunaan Sukrosa dan Penstabil Karboksi Metil Selulosa (CMC) terhadap Mutu dan Gingerol Jahe Instan
by: F Firdausni, et al.
Published: (2017-12-01)

Synthesis of Gingerol-Metals Complex and in-vitro Cytotoxic Activity on Human Colon Cancer Cell Line
by: Khdary NH, et al.
Published: (2023-01-01)

Phytochemical, Total Phenolic, and Antioxidant Activity of Ginger Extract and Its Use in the Synthesis of Eco-friendly Silver Nanoparticles
by: Abdulkadir Mohammed Noori Jassim, et al.
Published: (2023-10-01)

EFEKTIVITAS PEMBERIAN EKSTRAK JAHE MERAH (ZINGIBER OFFICINALE) TERHADAP JUMLAH SEL FIBROBLAS DALAM PROSES PENYEMBUHAN ULKUS PADA MUKOSA MULUT TIKUS PUTIH JANTAN (RATTUS NORVEGICUS)
by: Prima Agusmawanti
Published: (2016-12-01)

Purification and characterization of cationic peroxidase from ginger (Zingiber officinale)
by: Mohamed I. El-Khonezy, et al.
Published: (2020-01-01)

Gingerol and shogaol on red ginger rhizome (Zingiber officinale var. Rubrum) using high-performance liquid chromatography
by: Johan Sukweenadhi, et al.
Published: (2023-07-01)

The in vitro anti-Leishmania Effect of Zingiber officinale Extract on Promastigotes and Amastigotes of Leishmania major and Leishmania tropica
by: Jasem Saki, et al.
Published: (2022-06-01)

Drying ginger and preserving 6-gingerol
by: Li, LiZhuo, et al.
Published: (2018-11-01)

Effects of Zingiber Offcianille Essential Oil on Compressive Strength of Fluorescent Orthodontic Adhesive
by: Eman S. Al-Shihab, et al.
Published: (2024-04-01)

Characterization of Essential Oils and Fatty Acids Composition of Stored <i>Ginger</i> (<i>Zingiber officinale</i> Roscoe)
by: C.C. Oforma, et al.
Published: (2020-01-01)

Renoprotective effects of the ginger (Zingiber officinale) on Diabetic kidney disease, current knowledge and future direction: a systematic review of animal studies
by: Parisa Veisi, et al.
Published: (2022-11-01)

Zingiber officinale Rosc. essential oil, a review on its composition and bioactivity
by: Mohaddese Mahboubi
Published: (2019-01-01)

Anti-hyperlipidemic action of Zingiber officinale (Ginger) juice in alloxan induced diabetic rats
by: Selima Sultana, et al.
Published: (2012-07-01)

Protective Effect of Ginger on Gentamicin-Induced Apoptosis in Testis of Rats
by: Afshin Zahedi, et al.
Published: (2012-08-01)

Memory enhancement by administration of ginger (Zingiber officinale) extract on morphine-induced memory impairment in male rats
by: Ali Gomar, et al.
Published: (2014-01-01)

Immunomodulatory effects and mechanisms of the extracts and secondary compounds of Zingiber and Alpinia species: a review
by: Yuandani, et al.
Published: (2023-07-01)

Gingerols and shogaols: A multi-faceted review of their extraction, formulation, and analysis in drugs and biofluids to maximize their nutraceutical and pharmaceutical applications
by: Yasmin R. Maghraby, et al.
Published: (2023-12-01)

Determination of in vitro antidiabetic effects of Zingiber officinale Roscoe
by: Naila Abdul Sattar, et al.
Published: (2012-12-01)

Iron Chelation Property, Antioxidant Activity, and Hepatoprotective Effect of 6-Gingerol-Rich Ginger (<i>Zingiber officinale</i>) Extract in Iron-Loaded Huh7 Cells
by: Hataichanok Chuljerm, et al.
Published: (2023-08-01)

Do ginger footbaths improve symptoms of insomnia more than footbaths with warm water only? – A randomized controlled study
by: Silja Kuderer, et al.
Published: (2022-08-01)

Ginger (Zingiber officinale Roscoe)
by: Masoud Kavoli Haghighi, et al.
Published: (2002-03-01)

Assessment of antimicrobial potential of 10% ginger extract against Streptococcus mutans, Candida albicans, and Enterococcus faecalis: An in vitro study
by: Anjan Giriraju, et al.
Published: (2013-01-01)

Zingiber officinale Ethanolic Extract Attenuated Reserpine-Induced Depression-Like Condition and Associated Hippocampal Aberrations in Experimental Wistar Rats
by: Olanrewaju JA, et al.
Published: (2020-11-01)

The Gastro-protective Effect of Ginger (Zingiber officinale Roscoe) in Helicobacter pylori Positive Functional Dyspepsia
by: Vahideh Ebrahimzadeh Attari, et al.
Published: (2019-06-01)

Gas Chromatography-Mass Spectrometry Profile of Essential Oils Derived from Zingiber officinale Rosc. Rhizome
by: Noval Dwi Wijaya, et al.
Published: (2020-04-01)

In vitro lethal effect of Zingiber officinale R. on protoscolices of hydatid cyst from sheep liver
by: Mohammad Moazeni, et al.
Published: (2011-11-01)

10-Gingerol Inhibits Ovarian Cancer Cell Growth by Inducing G2 Arrest
by: Andrea Rasmussen, et al.
Published: (2019-10-01)

The Biological Function Prediction of The 10-gingerol Compound of Ginger in Inhibiting Cyclooxygenase-2 Activity
by: Gabriella Chandrakirana Krisnamurti, et al.
Published: (2020-12-01)

Preparation and Evaluation of 6-Gingerol Derivatives as Novel Antioxidants and Antiplatelet Agents
by: Sara H. H. Ahmed, et al.
Published: (2023-03-01)