Advances on the correlation between epilepsy and cortical spreading depression
Cortical spreading depression (CSD) is a pathological depolarization wave caused by the collective depolarization of neurons that propagates slowly along the cerebral cortex and can transiently inhibit brain electrical activity, which is related to a variety of paroxysmal encephalopathy. CSD and epi...
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| Format: | Article |
| Language: | English |
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Tianjin Huanhu Hospital
2023-05-01
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| Series: | Chinese Journal of Contemporary Neurology and Neurosurgery |
| Subjects: | |
| Online Access: | http://cjcnn.org/index.php/cjcnn/article/view/2695 |
| _version_ | 1797736292677582848 |
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| author | ZHANG Xu WANG Xiang⁃qing |
| author_facet | ZHANG Xu WANG Xiang⁃qing |
| author_sort | ZHANG Xu |
| collection | DOAJ |
| description | Cortical spreading depression (CSD) is a pathological depolarization wave caused by the collective depolarization of neurons that propagates slowly along the cerebral cortex and can transiently inhibit brain electrical activity, which is related to a variety of paroxysmal encephalopathy. CSD and epileptiform discharge are co ⁃ occurring electrophysiological phenomena. Factors causing CSD can also induce epileptic seizure. Inhibiting the occurrence and propagation of CSD may change the seizure threshold and reduce epileptic seizure, and the two are interrelated and interact on each other. This article reviews the research progress of the correlation between epilepsy and CSD, in order to improve the clinical understanding of the correlation between them. |
| first_indexed | 2024-03-12T13:11:33Z |
| format | Article |
| id | doaj.art-af8daf44f68345928d06efe084b10c27 |
| institution | Directory Open Access Journal |
| issn | 1672-6731 |
| language | English |
| last_indexed | 2024-03-12T13:11:33Z |
| publishDate | 2023-05-01 |
| publisher | Tianjin Huanhu Hospital |
| record_format | Article |
| series | Chinese Journal of Contemporary Neurology and Neurosurgery |
| spelling | doaj.art-af8daf44f68345928d06efe084b10c272023-08-28T01:02:28ZengTianjin Huanhu HospitalChinese Journal of Contemporary Neurology and Neurosurgery1672-67312023-05-0123546747110.3969/j.issn.1672-6731.2023.05.015Advances on the correlation between epilepsy and cortical spreading depressionZHANG Xu0WANG Xiang⁃qing1Department of Neurology, The First Medical Center of Chinese PLA General Hospital, Beijing 100853, ChinaDepartment of Neurology, The First Medical Center of Chinese PLA General Hospital, Beijing 100853, ChinaCortical spreading depression (CSD) is a pathological depolarization wave caused by the collective depolarization of neurons that propagates slowly along the cerebral cortex and can transiently inhibit brain electrical activity, which is related to a variety of paroxysmal encephalopathy. CSD and epileptiform discharge are co ⁃ occurring electrophysiological phenomena. Factors causing CSD can also induce epileptic seizure. Inhibiting the occurrence and propagation of CSD may change the seizure threshold and reduce epileptic seizure, and the two are interrelated and interact on each other. This article reviews the research progress of the correlation between epilepsy and CSD, in order to improve the clinical understanding of the correlation between them.http://cjcnn.org/index.php/cjcnn/article/view/2695epilepsycortical spreading depressionreview |
| spellingShingle | ZHANG Xu WANG Xiang⁃qing Advances on the correlation between epilepsy and cortical spreading depression Chinese Journal of Contemporary Neurology and Neurosurgery epilepsy cortical spreading depression review |
| title | Advances on the correlation between epilepsy and cortical spreading depression |
| title_full | Advances on the correlation between epilepsy and cortical spreading depression |
| title_fullStr | Advances on the correlation between epilepsy and cortical spreading depression |
| title_full_unstemmed | Advances on the correlation between epilepsy and cortical spreading depression |
| title_short | Advances on the correlation between epilepsy and cortical spreading depression |
| title_sort | advances on the correlation between epilepsy and cortical spreading depression |
| topic | epilepsy cortical spreading depression review |
| url | http://cjcnn.org/index.php/cjcnn/article/view/2695 |
| work_keys_str_mv | AT zhangxu advancesonthecorrelationbetweenepilepsyandcorticalspreadingdepression AT wangxiangqing advancesonthecorrelationbetweenepilepsyandcorticalspreadingdepression |