Enhancing immune responses of ESC-based TAA cancer vaccines with a novel OMV delivery system

Enhancing immune responses of ESC-based TAA cancer vaccines with a novel OMV delivery system

Abstract Embryonic stem cell (ESC)-derived epitopes can act as therapeutic tumor vaccines against different types of tumors Jin (Adv Healthc Mater 2023). However, these epitopes have poor immunogenicity and stimulate insufficient CD8+ T cell responses, which motivated us to develop a new method to d...

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Bibliographic Details
Main Authors: Meiling Jin, Da Huo, Jingjing Sun, Jingchu Hu, Shuzhen Liu, Mingshuo Zhan, Bao-zhong Zhang, Jian-Dong Huang
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Journal of Nanobiotechnology
Subjects:
Embryonic stem cell
Epitopes
Tumor immunity
OMVs
Vaccines
Online Access:https://doi.org/10.1186/s12951-023-02273-8

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