Growth differentiation factor 11 promotes macrophage polarization towards M2 to attenuate myocardial infarction via inhibiting Notch1 signaling pathway

Growth differentiation factor 11 promotes macrophage polarization towards M2 to attenuate myocardial infarction via inhibiting Notch1 signaling pathway

Myocardial infarctions (MI) is a major threat to human health especially in people exposed to cold environment. The polarization of macrophages towards different functional phenotypes (M1 macrophages and M2 macrophages) is closely related to MI repairment. The growth differentiation factor 11 (GDF11...

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Bibliographic Details
Main Authors: Gong Manyu, Yang Xuewen, Wang Yaqi, Wang Yanying, Liu Dongping, Li Haodong, Qu Yunmeng, Zhang Xiyang, Zhang Yanwei, Sun Han, Jiao Lei, Zhang Ying
Format: Article
Language:English
Published: Sciendo 2023-01-01
Series:Frigid Zone Medicine
Subjects:
myocardial infarction
growth differentiation factor 11
m1 macrophage
m2 macrophage
notch1
Online Access:https://doi.org/10.2478/fzm-2023-0008

Internet

https://doi.org/10.2478/fzm-2023-0008

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