Abdominal Ultrasound – The Leading Method in Duodenal Gist Diagnostics
Gastrointestinal stromal tumors (GIST) are the most common mesenchymal tumors of the digestive tract and are generally asymptomatic. A 39-year-old female patient was hospitalized in 2012 at Clinical Department of Internal Medicine, Sestre milosrdnice University Hospital Center, for a focal hypodense...
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| Format: | Article |
| Language: | English |
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Sestre Milosrdnice University hospital, Institute of Clinical Medical Research
2017-01-01
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| Series: | Acta Clinica Croatica |
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| Online Access: | https://hrcak.srce.hr/file/272417 |
| _version_ | 1797207831741464576 |
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| author | Sven Bohnec Ivan Budimir Davor Hrabar Nenad Babić Ivan Budimir Jr. Marko Nikolić Ivana Pavić |
| author_facet | Sven Bohnec Ivan Budimir Davor Hrabar Nenad Babić Ivan Budimir Jr. Marko Nikolić Ivana Pavić |
| author_sort | Sven Bohnec |
| collection | DOAJ |
| description | Gastrointestinal stromal tumors (GIST) are the most common mesenchymal tumors of the digestive tract and are generally asymptomatic. A 39-year-old female patient was hospitalized in 2012 at Clinical Department of Internal Medicine, Sestre milosrdnice University Hospital Center, for a focal hypodense irregular circular lesion located in segment III of the left hepatic lobe, accidentally found by ultrasonography and verified by computed tomography. Th e findings were also verified with nuclear magnetic resonance and esophagogastroduodenoscopy. A biopsy sample of the lesion was analyzed by histologic and immunohistochemical methods and identified as GIST. The patient underwent surgical operation (tumor excision with terminoterminal anastomosis created between the second segment of duodenum and jejunum and resection of liver segment III). The histopathologic findings matched GIST with a high probability of relapse according to the localization, size, mitotic activity and Ki-67 values. Th erefore, therapy with imatinib at a dose of 400 mg/day was administered. Three years after the operation, the patient is still in remission. |
| first_indexed | 2024-04-24T09:29:10Z |
| format | Article |
| id | doaj.art-af95f15ec91e4daf9ce77aa1c856a0cd |
| institution | Directory Open Access Journal |
| issn | 0353-9466 1333-9451 |
| language | English |
| last_indexed | 2024-04-24T09:29:10Z |
| publishDate | 2017-01-01 |
| publisher | Sestre Milosrdnice University hospital, Institute of Clinical Medical Research |
| record_format | Article |
| series | Acta Clinica Croatica |
| spelling | doaj.art-af95f15ec91e4daf9ce77aa1c856a0cd2024-04-15T14:17:23ZengSestre Milosrdnice University hospital, Institute of Clinical Medical ResearchActa Clinica Croatica0353-94661333-94512017-01-0156.1.18318710.20471/acc.2017.56.01.26Abdominal Ultrasound – The Leading Method in Duodenal Gist DiagnosticsSven Bohnec0Ivan Budimir1Davor Hrabar2Nenad Babić3Ivan Budimir Jr.4Marko Nikolić5Ivana Pavić6Gastroenterologie, Allgemeine Innere Medizin und Geriatrie, Rems-Murr Klinikum Winnenden, Winnenden, GermanyDepartment of Gastroenterology, Clinical Department of Internal Medicine, Sestre milosrdnice University Hospital Center, Zagreb, CroatiaDepartment of Gastroenterology, Clinical Department of Internal Medicine, Sestre milosrdnice University Hospital Center, Zagreb, CroatiaDivision of Radiology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia; School of Medicine and School of Dental Medicine, University of Zagreb, Zagreb, CroatiaMagdalena Hospital for Cardiovascular Diseases, Osijek School of Medicine, Krapinske TopliceDepartment of Gastroenterology, Clinical Department of Internal Medicine, Sestre milosrdnice University Hospital Center, Zagreb, CroatiaDepartment of Pathology, Sestre milosrdnice University Hospital Center, School of Medicine and School of Dental Medicine, University of Zagreb, Zagreb, CroatiaGastrointestinal stromal tumors (GIST) are the most common mesenchymal tumors of the digestive tract and are generally asymptomatic. A 39-year-old female patient was hospitalized in 2012 at Clinical Department of Internal Medicine, Sestre milosrdnice University Hospital Center, for a focal hypodense irregular circular lesion located in segment III of the left hepatic lobe, accidentally found by ultrasonography and verified by computed tomography. Th e findings were also verified with nuclear magnetic resonance and esophagogastroduodenoscopy. A biopsy sample of the lesion was analyzed by histologic and immunohistochemical methods and identified as GIST. The patient underwent surgical operation (tumor excision with terminoterminal anastomosis created between the second segment of duodenum and jejunum and resection of liver segment III). The histopathologic findings matched GIST with a high probability of relapse according to the localization, size, mitotic activity and Ki-67 values. Th erefore, therapy with imatinib at a dose of 400 mg/day was administered. Three years after the operation, the patient is still in remission.https://hrcak.srce.hr/file/272417Gastrointestinal stromal tumors – diagnostic imagingUltrasonographyElasticity imaging techniquesImatinib mesylateCase reports |
| spellingShingle | Sven Bohnec Ivan Budimir Davor Hrabar Nenad Babić Ivan Budimir Jr. Marko Nikolić Ivana Pavić Abdominal Ultrasound – The Leading Method in Duodenal Gist Diagnostics Acta Clinica Croatica Gastrointestinal stromal tumors – diagnostic imaging Ultrasonography Elasticity imaging techniques Imatinib mesylate Case reports |
| title | Abdominal Ultrasound – The Leading Method in Duodenal Gist Diagnostics |
| title_full | Abdominal Ultrasound – The Leading Method in Duodenal Gist Diagnostics |
| title_fullStr | Abdominal Ultrasound – The Leading Method in Duodenal Gist Diagnostics |
| title_full_unstemmed | Abdominal Ultrasound – The Leading Method in Duodenal Gist Diagnostics |
| title_short | Abdominal Ultrasound – The Leading Method in Duodenal Gist Diagnostics |
| title_sort | abdominal ultrasound the leading method in duodenal gist diagnostics |
| topic | Gastrointestinal stromal tumors – diagnostic imaging Ultrasonography Elasticity imaging techniques Imatinib mesylate Case reports |
| url | https://hrcak.srce.hr/file/272417 |
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