Serum, but Not Saliva, CXCL13 Levels Associate With Infiltrating CXCL13+ Cells in the Minor Salivary Gland Lesions and Other Histologic Parameters in Patients With Sjögren’s Syndrome

Serum, but Not Saliva, CXCL13 Levels Associate With Infiltrating CXCL13+ Cells in the Minor Salivary Gland Lesions and Other Histologic Parameters in Patients With Sjögren’s Syndrome

Recent studies suggest that elevated CXCL13 serum levels in patients with primary Sjögren’s syndrome (pSS) associate with minor salivary gland (MSG) histologic features, disease severity, as well as high-risk status for non-Hodgkin lymphoma (NHL) development and NHL itself. In contrast, limited disc...

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Bibliographic Details
Main Authors: Loukas Chatzis, Andreas V. Goules, Ioanna E. Stergiou, Michael Voulgarelis, Athanasios G. Tzioufas, Efstathia K. Kapsogeorgou
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Immunology
Subjects:
Sjögren’s syndrome
non-Hodgkin’s lymphoma
CXCL13 chemokine
serum
saliva
minor salivary gland
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.705079/full

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