Primary cardiac angiosarcoma: a case report
Primary cardiac angiosarcoma is relatively rare, and most cases involve metastasis at the time of diagnosis. The median survival time is 14 months for patients who can be treated surgically, versus 3.8 ± 2.5 months for patients with metastasis who could not undergo surgery. Radical surgical resectio...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2021-08-01
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| Series: | Journal of International Medical Research |
| Online Access: | https://doi.org/10.1177/03000605211033261 |
| _version_ | 1819124632471470080 |
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| author | Xin Fang Song Zheng |
| author_facet | Xin Fang Song Zheng |
| author_sort | Xin Fang |
| collection | DOAJ |
| description | Primary cardiac angiosarcoma is relatively rare, and most cases involve metastasis at the time of diagnosis. The median survival time is 14 months for patients who can be treated surgically, versus 3.8 ± 2.5 months for patients with metastasis who could not undergo surgery. Radical surgical resection, radiotherapy, chemotherapy, and targeted therapy are the main treatments, but prognosis remains poor because of rapid progression and high recurrence and metastasis rates. At present, there is no unified standard treatment, and selecting the correct treatment plan and improving patient survival and quality of life remain challenging. We have reported the case of a 45-year-old woman with a primary heart tumor that infiltrated the right atrial wall and pericardium. Angiosarcoma was verified histologically. After palliative resection of the primary tumor followed by concurrent chemoradiotherapy and targeted therapy, the patient exhibited overall survival of 23 months, highlighting the potential utility of this treatment strategy. |
| first_indexed | 2024-12-22T07:27:20Z |
| format | Article |
| id | doaj.art-af9e12d142d9451db080e2356794a782 |
| institution | Directory Open Access Journal |
| issn | 1473-2300 |
| language | English |
| last_indexed | 2024-12-22T07:27:20Z |
| publishDate | 2021-08-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of International Medical Research |
| spelling | doaj.art-af9e12d142d9451db080e2356794a7822022-12-21T18:34:06ZengSAGE PublishingJournal of International Medical Research1473-23002021-08-014910.1177/03000605211033261Primary cardiac angiosarcoma: a case reportXin FangSong ZhengPrimary cardiac angiosarcoma is relatively rare, and most cases involve metastasis at the time of diagnosis. The median survival time is 14 months for patients who can be treated surgically, versus 3.8 ± 2.5 months for patients with metastasis who could not undergo surgery. Radical surgical resection, radiotherapy, chemotherapy, and targeted therapy are the main treatments, but prognosis remains poor because of rapid progression and high recurrence and metastasis rates. At present, there is no unified standard treatment, and selecting the correct treatment plan and improving patient survival and quality of life remain challenging. We have reported the case of a 45-year-old woman with a primary heart tumor that infiltrated the right atrial wall and pericardium. Angiosarcoma was verified histologically. After palliative resection of the primary tumor followed by concurrent chemoradiotherapy and targeted therapy, the patient exhibited overall survival of 23 months, highlighting the potential utility of this treatment strategy.https://doi.org/10.1177/03000605211033261 |
| spellingShingle | Xin Fang Song Zheng Primary cardiac angiosarcoma: a case report Journal of International Medical Research |
| title | Primary cardiac angiosarcoma: a case report |
| title_full | Primary cardiac angiosarcoma: a case report |
| title_fullStr | Primary cardiac angiosarcoma: a case report |
| title_full_unstemmed | Primary cardiac angiosarcoma: a case report |
| title_short | Primary cardiac angiosarcoma: a case report |
| title_sort | primary cardiac angiosarcoma a case report |
| url | https://doi.org/10.1177/03000605211033261 |
| work_keys_str_mv | AT xinfang primarycardiacangiosarcomaacasereport AT songzheng primarycardiacangiosarcomaacasereport |