Gold Nanoparticles Disrupt the IGFBP2/mTOR/PTEN Axis to Inhibit Ovarian Cancer Growth

Gold Nanoparticles Disrupt the IGFBP2/mTOR/PTEN Axis to Inhibit Ovarian Cancer Growth

Abstract By exploiting the self‐therapeutic properties of gold nanoparticles (GNPs) a molecular axis that promotes the growth of high‐grade serous ovarian cancer (HGSOC), one of the deadliest gynecologic malignancies with poorly understood underlying molecular mechanisms, has been identified. The bi...

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Bibliographic Details
Main Authors: Md. Nazir Hossen, Lin Wang, Shailendra Kumar Dhar Dwivedi, Yushan Zhang, Geeta Rao, Chandra Kumar Elechalwar, Vinit Sheth, Anindya Dey, Sima Asfa, Suresh Kumar Gulla, Chao Xu, Kar‐Ming Fung, J. David Robertson, Magdalena Bieniasz, Stefan Wilhelm, Resham Bhattacharya, Priyabrata Mukherjee
Format: Article
Language:English
Published: Wiley 2022-11-01
Series:Advanced Science
Subjects:
gold nanoparticles
IGFBP2
IGFBP2/PTEN autoregulation
ovarian cancer
tumor therapy
Online Access:https://doi.org/10.1002/advs.202200491

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