873 ISM5939, a novel, potent, orally available, selective ENPP1 inhibitor enhances the anti-tumor effects of immune checkpoint inhibitors in syngeneic murine cancer models

Bibliographic Details
Main Authors: Man Zhang, Jin Liu, Celia Chen, Xin Cheng, Feng Ren, Jianyu Wu, Luoheng Qin, Supriya Bavadekar, Sujata Rao, Alex Zhavoronkov
Format: Article
Language:English
Published: BMJ Publishing Group 2023-11-01
Series:Journal for ImmunoTherapy of Cancer
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author Man Zhang
Jin Liu
Celia Chen
Xin Cheng
Feng Ren
Jianyu Wu
Luoheng Qin
Supriya Bavadekar
Sujata Rao
Alex Zhavoronkov
author_facet Man Zhang
Jin Liu
Celia Chen
Xin Cheng
Feng Ren
Jianyu Wu
Luoheng Qin
Supriya Bavadekar
Sujata Rao
Alex Zhavoronkov
author_sort Man Zhang
collection DOAJ
first_indexed 2024-03-08T21:34:31Z
format Article
id doaj.art-afae6751e3974d32a370e307ea370e76
institution Directory Open Access Journal
issn 2051-1426
language English
last_indexed 2024-03-08T21:34:31Z
publishDate 2023-11-01
publisher BMJ Publishing Group
record_format Article
series Journal for ImmunoTherapy of Cancer
spelling doaj.art-afae6751e3974d32a370e307ea370e762023-12-21T01:25:08ZengBMJ Publishing GroupJournal for ImmunoTherapy of Cancer2051-14262023-11-0111Suppl 110.1136/jitc-2023-SITC2023.0873873 ISM5939, a novel, potent, orally available, selective ENPP1 inhibitor enhances the anti-tumor effects of immune checkpoint inhibitors in syngeneic murine cancer modelsMan Zhang0Jin Liu1Celia Chen2Xin Cheng3Feng Ren4Jianyu Wu5Luoheng Qin6Supriya Bavadekar7Sujata Rao8Alex Zhavoronkov9Department of Hematology, Harbin Medical University Cancer Hospital, Harbin Medical University, Harbin, Heilongjiang, China1Insilico Medicine, Shanghai, China1Insilico Medicine, Shanghai, China1Insilico Medicine, Shanghai, China1Insilico Medicine, Shanghai, China1Insilico Medicine, Shanghai, China1Insilico Medicine, Shanghai, China2Insilico Medicine, New York, NY, USA2Insilico Medicine, New York, NY, USA1Insilico Medicine, Shanghai, China
spellingShingle Man Zhang
Jin Liu
Celia Chen
Xin Cheng
Feng Ren
Jianyu Wu
Luoheng Qin
Supriya Bavadekar
Sujata Rao
Alex Zhavoronkov
873 ISM5939, a novel, potent, orally available, selective ENPP1 inhibitor enhances the anti-tumor effects of immune checkpoint inhibitors in syngeneic murine cancer models
Journal for ImmunoTherapy of Cancer
title 873 ISM5939, a novel, potent, orally available, selective ENPP1 inhibitor enhances the anti-tumor effects of immune checkpoint inhibitors in syngeneic murine cancer models
title_full 873 ISM5939, a novel, potent, orally available, selective ENPP1 inhibitor enhances the anti-tumor effects of immune checkpoint inhibitors in syngeneic murine cancer models
title_fullStr 873 ISM5939, a novel, potent, orally available, selective ENPP1 inhibitor enhances the anti-tumor effects of immune checkpoint inhibitors in syngeneic murine cancer models
title_full_unstemmed 873 ISM5939, a novel, potent, orally available, selective ENPP1 inhibitor enhances the anti-tumor effects of immune checkpoint inhibitors in syngeneic murine cancer models
title_short 873 ISM5939, a novel, potent, orally available, selective ENPP1 inhibitor enhances the anti-tumor effects of immune checkpoint inhibitors in syngeneic murine cancer models
title_sort 873 ism5939 a novel potent orally available selective enpp1 inhibitor enhances the anti tumor effects of immune checkpoint inhibitors in syngeneic murine cancer models
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