Societal Costs of Moderate-to-severe Atopic Dermatitis Occurring in Adulthood: A Danish Register-based Study

To estimate the cost of illness in adult patients with moderate-to-severe atopic dermatitis (AD) a cohort study was conducted identifying Danish citizens (≥ 18 years) diagnosed with AD between 1997 and 2018 in the Danish National Patient Register. Moderate-to-severe AD was defined as ≥3 hospital con...

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Main Authors: Jacob P. Thyssen, Andreas W. Brenneche, Maria E. Madsen, Mikkel H. Pedersen, Dennis J. Trangbaek, Christian Vestergaard
Format: Article
Language:English
Published: Medical Journals Sweden 2021-09-01
Series:Acta Dermato-Venereologica
Subjects:
Online Access: https://www.medicaljournals.se/acta/content/html/10.2340/00015555-3908
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author Jacob P. Thyssen
Andreas W. Brenneche
Maria E. Madsen
Mikkel H. Pedersen
Dennis J. Trangbaek
Christian Vestergaard
author_facet Jacob P. Thyssen
Andreas W. Brenneche
Maria E. Madsen
Mikkel H. Pedersen
Dennis J. Trangbaek
Christian Vestergaard
author_sort Jacob P. Thyssen
collection DOAJ
description To estimate the cost of illness in adult patients with moderate-to-severe atopic dermatitis (AD) a cohort study was conducted identifying Danish citizens (≥ 18 years) diagnosed with AD between 1997 and 2018 in the Danish National Patient Register. Moderate-to-severe AD was defined as ≥3 hospital contacts regarding AD the first year after  diagnosis. Each patient with AD was matched to 3 reference individuals through the Central Person Registry. Societal costs included the direct costs for primary-sector visits, inpatient hospitalizations, outpatient contacts, prescription medicine and indirect costs of lost productivity 3 years before and 5 years after the index date (the study period). A total of 5,245 patients with moderate-to-severe AD were identified. The mean attributable healthcare costs for patients with moderate-to-severe AD were EUR 10,835 (p < 0.0001) during the study period. Moderate-to-severe AD among adults inferred substantial economic burden compared with a group of matched reference individuals.
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spelling doaj.art-afaff49eb5314672b6125094c4887ebc2022-12-21T23:49:39ZengMedical Journals SwedenActa Dermato-Venereologica0001-55551651-20572021-09-011019adv0053810.2340/00015555-39087052Societal Costs of Moderate-to-severe Atopic Dermatitis Occurring in Adulthood: A Danish Register-based StudyJacob P. Thyssen0Andreas W. BrennecheMaria E. MadsenMikkel H. PedersenDennis J. TrangbaekChristian Vestergaard Department of Dermatology and Venereology, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark. To estimate the cost of illness in adult patients with moderate-to-severe atopic dermatitis (AD) a cohort study was conducted identifying Danish citizens (≥ 18 years) diagnosed with AD between 1997 and 2018 in the Danish National Patient Register. Moderate-to-severe AD was defined as ≥3 hospital contacts regarding AD the first year after  diagnosis. Each patient with AD was matched to 3 reference individuals through the Central Person Registry. Societal costs included the direct costs for primary-sector visits, inpatient hospitalizations, outpatient contacts, prescription medicine and indirect costs of lost productivity 3 years before and 5 years after the index date (the study period). A total of 5,245 patients with moderate-to-severe AD were identified. The mean attributable healthcare costs for patients with moderate-to-severe AD were EUR 10,835 (p < 0.0001) during the study period. Moderate-to-severe AD among adults inferred substantial economic burden compared with a group of matched reference individuals. https://www.medicaljournals.se/acta/content/html/10.2340/00015555-3908 atopic dermatitis burden of disease cost of illness real-world evidence register-based cohort study
spellingShingle Jacob P. Thyssen
Andreas W. Brenneche
Maria E. Madsen
Mikkel H. Pedersen
Dennis J. Trangbaek
Christian Vestergaard
Societal Costs of Moderate-to-severe Atopic Dermatitis Occurring in Adulthood: A Danish Register-based Study
Acta Dermato-Venereologica
atopic dermatitis
burden of disease
cost of illness
real-world evidence
register-based cohort study
title Societal Costs of Moderate-to-severe Atopic Dermatitis Occurring in Adulthood: A Danish Register-based Study
title_full Societal Costs of Moderate-to-severe Atopic Dermatitis Occurring in Adulthood: A Danish Register-based Study
title_fullStr Societal Costs of Moderate-to-severe Atopic Dermatitis Occurring in Adulthood: A Danish Register-based Study
title_full_unstemmed Societal Costs of Moderate-to-severe Atopic Dermatitis Occurring in Adulthood: A Danish Register-based Study
title_short Societal Costs of Moderate-to-severe Atopic Dermatitis Occurring in Adulthood: A Danish Register-based Study
title_sort societal costs of moderate to severe atopic dermatitis occurring in adulthood a danish register based study
topic atopic dermatitis
burden of disease
cost of illness
real-world evidence
register-based cohort study
url https://www.medicaljournals.se/acta/content/html/10.2340/00015555-3908
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