Pituitary pars intermedia dysfunction in horses associated to pituitary adenoma
ABSTRACT: The clinical syndrome of the pituitary pars intermedia dysfunction (PPID) is the most common endocrinopathy of older horses. This syndrome is characterized by several clinical and pathological changes, which are usually associated with adenomas of the pars intermedia (PI) of the pituitary...
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| Format: | Article |
| Language: | English |
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Colégio Brasileiro de Patologia Animal (CBPA)
2023-02-01
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| Series: | Pesquisa Veterinária Brasileira |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-736X2023000100206&lng=en&tlng=en |
| _version_ | 1811170360303812608 |
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| author | Anderson H. Gris Ronaldo M. Bianchi Claiton I. Schwertz Manoela M. Piva Gabriela Richter Luciana Sonne David Driemeier Saulo P. Pavarini |
| author_facet | Anderson H. Gris Ronaldo M. Bianchi Claiton I. Schwertz Manoela M. Piva Gabriela Richter Luciana Sonne David Driemeier Saulo P. Pavarini |
| author_sort | Anderson H. Gris |
| collection | DOAJ |
| description | ABSTRACT: The clinical syndrome of the pituitary pars intermedia dysfunction (PPID) is the most common endocrinopathy of older horses. This syndrome is characterized by several clinical and pathological changes, which are usually associated with adenomas of the pars intermedia (PI) of the pituitary gland. The aim of this work is to describe five cases of pituitary adenoma of the PI associated with PPID in horses, addressing its clinical and pathological aspects. The horses had a mean of 22 years of age. The main clinical signs were hirsutism and paresis of hind limbs, and at post mortem examination all horses had hirsutism, and a nodule in the pituitary gland, which was histologically characterized as an adenoma of PI (5/5). Furthermore, two horses had gross lesions suggestive of chronic laminitis. Moreover, there was intense parasitism of Sarcocystis neurona (2/5), Strongylus vulgaris (1/5), Parascaris equorum (1/5), Draschia megastoma (1/5), and Klossiella equi (1/5). |
| first_indexed | 2024-04-10T16:56:42Z |
| format | Article |
| id | doaj.art-afb39ede106a4b95b5b770e633a566de |
| institution | Directory Open Access Journal |
| issn | 1678-5150 |
| language | English |
| last_indexed | 2024-04-10T16:56:42Z |
| publishDate | 2023-02-01 |
| publisher | Colégio Brasileiro de Patologia Animal (CBPA) |
| record_format | Article |
| series | Pesquisa Veterinária Brasileira |
| spelling | doaj.art-afb39ede106a4b95b5b770e633a566de2023-02-07T07:33:12ZengColégio Brasileiro de Patologia Animal (CBPA)Pesquisa Veterinária Brasileira1678-51502023-02-014310.1590/1678-5150-pvb-7117Pituitary pars intermedia dysfunction in horses associated to pituitary adenomaAnderson H. Grishttps://orcid.org/0000-0002-3926-9491Ronaldo M. Bianchihttps://orcid.org/0000-0001-9187-486XClaiton I. Schwertzhttps://orcid.org/0000-0002-5285-7896Manoela M. Pivahttps://orcid.org/0000-0002-1484-2220Gabriela Richterhttps://orcid.org/0000-0002-2847-7914Luciana Sonnehttps://orcid.org/0000-0003-3101-8134David Driemeierhttps://orcid.org/0000-0003-3766-0654Saulo P. Pavarinihttps://orcid.org/0000-0001-8980-6294ABSTRACT: The clinical syndrome of the pituitary pars intermedia dysfunction (PPID) is the most common endocrinopathy of older horses. This syndrome is characterized by several clinical and pathological changes, which are usually associated with adenomas of the pars intermedia (PI) of the pituitary gland. The aim of this work is to describe five cases of pituitary adenoma of the PI associated with PPID in horses, addressing its clinical and pathological aspects. The horses had a mean of 22 years of age. The main clinical signs were hirsutism and paresis of hind limbs, and at post mortem examination all horses had hirsutism, and a nodule in the pituitary gland, which was histologically characterized as an adenoma of PI (5/5). Furthermore, two horses had gross lesions suggestive of chronic laminitis. Moreover, there was intense parasitism of Sarcocystis neurona (2/5), Strongylus vulgaris (1/5), Parascaris equorum (1/5), Draschia megastoma (1/5), and Klossiella equi (1/5).http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-736X2023000100206&lng=en&tlng=enPPIDhypothalamusparasitismhirsutismlaminitishorsesequine |
| spellingShingle | Anderson H. Gris Ronaldo M. Bianchi Claiton I. Schwertz Manoela M. Piva Gabriela Richter Luciana Sonne David Driemeier Saulo P. Pavarini Pituitary pars intermedia dysfunction in horses associated to pituitary adenoma Pesquisa Veterinária Brasileira PPID hypothalamus parasitism hirsutism laminitis horses equine |
| title | Pituitary pars intermedia dysfunction in horses associated to pituitary adenoma |
| title_full | Pituitary pars intermedia dysfunction in horses associated to pituitary adenoma |
| title_fullStr | Pituitary pars intermedia dysfunction in horses associated to pituitary adenoma |
| title_full_unstemmed | Pituitary pars intermedia dysfunction in horses associated to pituitary adenoma |
| title_short | Pituitary pars intermedia dysfunction in horses associated to pituitary adenoma |
| title_sort | pituitary pars intermedia dysfunction in horses associated to pituitary adenoma |
| topic | PPID hypothalamus parasitism hirsutism laminitis horses equine |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-736X2023000100206&lng=en&tlng=en |
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