Electrocardiographic and echocardiographic predictors of greater carotid intima‐media thickness in tactical athletes: The CHIEF atherosclerosis study
Abstract Objective Both electrocardiographic and echocardiographic left ventricular hypertrophy (LVH) have been reported with an association with greater carotid intima‐media thickness (cIMT), a marker of subclinical atherosclerosis in patients with hypertension, while the associations are unclear i...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2023-03-01
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| Series: | Annals of Noninvasive Electrocardiology |
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| Online Access: | https://doi.org/10.1111/anec.13045 |
| _version_ | 1797867546216497152 |
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| author | Yen‐Po Lin Yi‐Chiung Hsu Kun‐Zhe Tsai Wei‐Chun Huang Chih‐Lu Han Gen‐Min Lin |
| author_facet | Yen‐Po Lin Yi‐Chiung Hsu Kun‐Zhe Tsai Wei‐Chun Huang Chih‐Lu Han Gen‐Min Lin |
| author_sort | Yen‐Po Lin |
| collection | DOAJ |
| description | Abstract Objective Both electrocardiographic and echocardiographic left ventricular hypertrophy (LVH) have been reported with an association with greater carotid intima‐media thickness (cIMT), a marker of subclinical atherosclerosis in patients with hypertension, while the associations are unclear in physically fit young adults. Methods A total of 1822 Taiwanese military personnel, aged 18–40 years, received an annual health examination including electrocardiography (ECG) and echocardiography in 2018–2020. Left carotid bulb cIMT was measured by high‐resolution ultrasonography. Multiple logistic regression analysis with adjustments for age, sex, smoking, alcohol consumption, body mass index, mean blood pressure, and physical fitness was used to determine the associations between echocardiographic and ECG parameters and the highest quintile of cIMT (≥0.8 mm). Results Cornell‐based LVH, Myers et al.‐based RVH and heart rate ≥75/min were associated with cIMT ≥0.8 mm [odds ratios (ORs) and 95% confidence intervals: 1.54 (1.01, 2.35), 1.66 (1.18, 2.33), and 1.39 (1.06, 1.83), respectively], while echocardiographic LVH defined as ≥46.0 g/m2.7 for men and ≥38.0 g/m2.7 for women was inversely associated with cIMT ≥0.8 mm [OR: 0.45 (0.24, 0.86)]. Conclusion In tactical athletes of military, the associations of ECG and echocardiographic LVH with cIMT were in opposite directions. Higher physical fitness may cause cardiac muscle hypertrophy and reduce the atherosclerosis severity, possibly leading to the paradoxical echocardiographic finding. This study suggests that ECG‐based LVH remains a good marker of subclinical atherosclerosis in our military population. |
| first_indexed | 2024-04-09T23:41:52Z |
| format | Article |
| id | doaj.art-afb58f4da5e1412a833671305059dd01 |
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| issn | 1082-720X 1542-474X |
| language | English |
| last_indexed | 2024-04-09T23:41:52Z |
| publishDate | 2023-03-01 |
| publisher | Wiley |
| record_format | Article |
| series | Annals of Noninvasive Electrocardiology |
| spelling | doaj.art-afb58f4da5e1412a833671305059dd012023-03-18T05:46:03ZengWileyAnnals of Noninvasive Electrocardiology1082-720X1542-474X2023-03-01282n/an/a10.1111/anec.13045Electrocardiographic and echocardiographic predictors of greater carotid intima‐media thickness in tactical athletes: The CHIEF atherosclerosis studyYen‐Po Lin0Yi‐Chiung Hsu1Kun‐Zhe Tsai2Wei‐Chun Huang3Chih‐Lu Han4Gen‐Min Lin5Department of Biomedical Sciences & Engineering National Central University Taoyuan TaiwanDepartment of Biomedical Sciences & Engineering National Central University Taoyuan TaiwanDepartment of Stomatology of Periodontology Mackay Memorial Hospital Taipei TaiwanCollege of Medicine National Yang Ming Chiao Tung University Taipei TaiwanDepartment of Internal Medicine Taipei Veterans General Hospital Taipei TaiwanDepartment of Biomedical Sciences & Engineering National Central University Taoyuan TaiwanAbstract Objective Both electrocardiographic and echocardiographic left ventricular hypertrophy (LVH) have been reported with an association with greater carotid intima‐media thickness (cIMT), a marker of subclinical atherosclerosis in patients with hypertension, while the associations are unclear in physically fit young adults. Methods A total of 1822 Taiwanese military personnel, aged 18–40 years, received an annual health examination including electrocardiography (ECG) and echocardiography in 2018–2020. Left carotid bulb cIMT was measured by high‐resolution ultrasonography. Multiple logistic regression analysis with adjustments for age, sex, smoking, alcohol consumption, body mass index, mean blood pressure, and physical fitness was used to determine the associations between echocardiographic and ECG parameters and the highest quintile of cIMT (≥0.8 mm). Results Cornell‐based LVH, Myers et al.‐based RVH and heart rate ≥75/min were associated with cIMT ≥0.8 mm [odds ratios (ORs) and 95% confidence intervals: 1.54 (1.01, 2.35), 1.66 (1.18, 2.33), and 1.39 (1.06, 1.83), respectively], while echocardiographic LVH defined as ≥46.0 g/m2.7 for men and ≥38.0 g/m2.7 for women was inversely associated with cIMT ≥0.8 mm [OR: 0.45 (0.24, 0.86)]. Conclusion In tactical athletes of military, the associations of ECG and echocardiographic LVH with cIMT were in opposite directions. Higher physical fitness may cause cardiac muscle hypertrophy and reduce the atherosclerosis severity, possibly leading to the paradoxical echocardiographic finding. This study suggests that ECG‐based LVH remains a good marker of subclinical atherosclerosis in our military population.https://doi.org/10.1111/anec.13045carotid intima‐media thicknessechocardiographyelectrocardiographymilitary personneltactical athletes |
| spellingShingle | Yen‐Po Lin Yi‐Chiung Hsu Kun‐Zhe Tsai Wei‐Chun Huang Chih‐Lu Han Gen‐Min Lin Electrocardiographic and echocardiographic predictors of greater carotid intima‐media thickness in tactical athletes: The CHIEF atherosclerosis study Annals of Noninvasive Electrocardiology carotid intima‐media thickness echocardiography electrocardiography military personnel tactical athletes |
| title | Electrocardiographic and echocardiographic predictors of greater carotid intima‐media thickness in tactical athletes: The CHIEF atherosclerosis study |
| title_full | Electrocardiographic and echocardiographic predictors of greater carotid intima‐media thickness in tactical athletes: The CHIEF atherosclerosis study |
| title_fullStr | Electrocardiographic and echocardiographic predictors of greater carotid intima‐media thickness in tactical athletes: The CHIEF atherosclerosis study |
| title_full_unstemmed | Electrocardiographic and echocardiographic predictors of greater carotid intima‐media thickness in tactical athletes: The CHIEF atherosclerosis study |
| title_short | Electrocardiographic and echocardiographic predictors of greater carotid intima‐media thickness in tactical athletes: The CHIEF atherosclerosis study |
| title_sort | electrocardiographic and echocardiographic predictors of greater carotid intima media thickness in tactical athletes the chief atherosclerosis study |
| topic | carotid intima‐media thickness echocardiography electrocardiography military personnel tactical athletes |
| url | https://doi.org/10.1111/anec.13045 |
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