The transcriptome profile of human trisomy 21 blood cells

Abstract Background Trisomy 21 (T21) is a genetic alteration characterised by the presence of an extra full or partial human chromosome 21 (Hsa21) leading to Down syndrome (DS), the most common form of intellectual disability (ID). It is broadly agreed that the presence of extra genetic material in...

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Bibliographic Details
Main Authors:	Francesca Antonaros, Rossella Zenatelli, Giulia Guerri, Matteo Bertelli, Chiara Locatelli, Beatrice Vione, Francesca Catapano, Alice Gori, Lorenza Vitale, Maria Chiara Pelleri, Giuseppe Ramacieri, Guido Cocchi, Pierluigi Strippoli, Maria Caracausi, Allison Piovesan
Format:	Article
Language:	English
Published:	BMC 2021-05-01
Series:	Human Genomics
Subjects:	Transcriptome RNA sequencing Blood cells Human chromosome 21 Trisomy 21 Down syndrome
Online Access:	https://doi.org/10.1186/s40246-021-00325-4

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