In vitro, in vivo, and clinical tests of a novel flexible ureteroscope for the diagnosis and treatment of kidney and ureteral diseases
Purpose: Despite advances in flexible ureteroscopy, the high cost and long repair time of ureteroscopes limit their use in the urology. We compared the performance of a novel flexible ureteroscope (fURS) ‘HF-EH’ with that of the two contemporary fURSs ‘URF-P6’ and ‘COBRA’. Materials and Methods: We...
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| Format: | Article |
| Language: | English |
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Korean Urological Association
2018-09-01
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| Series: | Investigative and Clinical Urology |
| Subjects: | |
| Online Access: | https://www.icurology.org/Synapse/Data/PDFData/2020ICU/icu-59-328.pdf |
| _version_ | 1828946270658494464 |
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| author | Dai Hee Kim Jung Hyun Shin Se Young Choi Dalsan You Choung-Soo Kim Hyung Keun Park |
| author_facet | Dai Hee Kim Jung Hyun Shin Se Young Choi Dalsan You Choung-Soo Kim Hyung Keun Park |
| author_sort | Dai Hee Kim |
| collection | DOAJ |
| description | Purpose: Despite advances in flexible ureteroscopy, the high cost and long repair time of ureteroscopes limit their use in the urology. We compared the performance of a novel flexible ureteroscope (fURS) ‘HF-EH’ with that of the two contemporary fURSs ‘URF-P6’ and ‘COBRA’. Materials and Methods: We compared in vitro measurements of deflection angle, irrigation flow rate, and image quality between HF-EH and URF-P6 while also inspecting renal collecting systems in five female pigs. For clinical testing, we performed retrograde intrarenal surgeries using HF-EH in four patients. Experienced urologists compared performance parameters (irrigation, convenience, and maneuverability) between the HF-EH and COBRA. Results: The flow rate of HF-EH (21.0 mL/min) was worse, and its resolution (1.59 line pairs/mm) was inferior to that of URF-P6 (28.7 mL/min and 3.17 line pairs/mm, respectively). However, HF-EH was superior to URF-P6 in terms of loss of deflection angle with the insertion of accessories (1.8% vs. 12.7%). In vivo and clinical testing revealed that the performance parameters of HF-EH were slightly inferior to those of conventional domestic fURSs. We successfully performed retrograde intrarenal surgeries using HF-EH in four patients and achieved stone-free statuses in two. None of the patients exhibited any procedure-related complications. Conclusions: Although we observed that two of the three performance parameters of the novel ureteroscope ‘HF-EH’ were inferior to those of the conventional ureteroscope, we successfully used HF-EH to perform retrograde intrarenal surgeries in patients. Further studies on performance and durability are warranted for making HF-EH commercially available. |
| first_indexed | 2024-12-14T05:07:37Z |
| format | Article |
| id | doaj.art-afb923c99ab24e458f9f217b05efa94e |
| institution | Directory Open Access Journal |
| issn | 2466-0493 2466-054X |
| language | English |
| last_indexed | 2024-12-14T05:07:37Z |
| publishDate | 2018-09-01 |
| publisher | Korean Urological Association |
| record_format | Article |
| series | Investigative and Clinical Urology |
| spelling | doaj.art-afb923c99ab24e458f9f217b05efa94e2022-12-21T23:16:04ZengKorean Urological AssociationInvestigative and Clinical Urology2466-04932466-054X2018-09-0159532833410.4111/icu.2018.59.5.328In vitro, in vivo, and clinical tests of a novel flexible ureteroscope for the diagnosis and treatment of kidney and ureteral diseasesDai Hee Kim0Jung Hyun Shin1Se Young Choi2Dalsan You3Choung-Soo Kim4Hyung Keun Park5Asan Medical Center, University of Ulsan College of Medicine, Seoul, KoreaAsan Medical Center, University of Ulsan College of Medicine, Seoul, KoreaAsan Medical Center, University of Ulsan College of Medicine, Seoul, KoreaAsan Medical Center, University of Ulsan College of Medicine, Seoul, KoreaAsan Medical Center, University of Ulsan College of Medicine, Seoul, KoreaAsan Medical Center, University of Ulsan College of Medicine, Seoul, KoreaPurpose: Despite advances in flexible ureteroscopy, the high cost and long repair time of ureteroscopes limit their use in the urology. We compared the performance of a novel flexible ureteroscope (fURS) ‘HF-EH’ with that of the two contemporary fURSs ‘URF-P6’ and ‘COBRA’. Materials and Methods: We compared in vitro measurements of deflection angle, irrigation flow rate, and image quality between HF-EH and URF-P6 while also inspecting renal collecting systems in five female pigs. For clinical testing, we performed retrograde intrarenal surgeries using HF-EH in four patients. Experienced urologists compared performance parameters (irrigation, convenience, and maneuverability) between the HF-EH and COBRA. Results: The flow rate of HF-EH (21.0 mL/min) was worse, and its resolution (1.59 line pairs/mm) was inferior to that of URF-P6 (28.7 mL/min and 3.17 line pairs/mm, respectively). However, HF-EH was superior to URF-P6 in terms of loss of deflection angle with the insertion of accessories (1.8% vs. 12.7%). In vivo and clinical testing revealed that the performance parameters of HF-EH were slightly inferior to those of conventional domestic fURSs. We successfully performed retrograde intrarenal surgeries using HF-EH in four patients and achieved stone-free statuses in two. None of the patients exhibited any procedure-related complications. Conclusions: Although we observed that two of the three performance parameters of the novel ureteroscope ‘HF-EH’ were inferior to those of the conventional ureteroscope, we successfully used HF-EH to perform retrograde intrarenal surgeries in patients. Further studies on performance and durability are warranted for making HF-EH commercially available.https://www.icurology.org/Synapse/Data/PDFData/2020ICU/icu-59-328.pdfLithotripsyNephrolithiasisUreteroscopes |
| spellingShingle | Dai Hee Kim Jung Hyun Shin Se Young Choi Dalsan You Choung-Soo Kim Hyung Keun Park In vitro, in vivo, and clinical tests of a novel flexible ureteroscope for the diagnosis and treatment of kidney and ureteral diseases Investigative and Clinical Urology Lithotripsy Nephrolithiasis Ureteroscopes |
| title | In vitro, in vivo, and clinical tests of a novel flexible ureteroscope for the diagnosis and treatment of kidney and ureteral diseases |
| title_full | In vitro, in vivo, and clinical tests of a novel flexible ureteroscope for the diagnosis and treatment of kidney and ureteral diseases |
| title_fullStr | In vitro, in vivo, and clinical tests of a novel flexible ureteroscope for the diagnosis and treatment of kidney and ureteral diseases |
| title_full_unstemmed | In vitro, in vivo, and clinical tests of a novel flexible ureteroscope for the diagnosis and treatment of kidney and ureteral diseases |
| title_short | In vitro, in vivo, and clinical tests of a novel flexible ureteroscope for the diagnosis and treatment of kidney and ureteral diseases |
| title_sort | in vitro in vivo and clinical tests of a novel flexible ureteroscope for the diagnosis and treatment of kidney and ureteral diseases |
| topic | Lithotripsy Nephrolithiasis Ureteroscopes |
| url | https://www.icurology.org/Synapse/Data/PDFData/2020ICU/icu-59-328.pdf |
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