Biocompatibility evaluation of an antibiotic paste after pulpotomy in dogs
The purpose of this study was to evaluate by histological analysis, the biocompatibility of an antibiotic paste following treatment of pulpotomies in dogs. Four male adult dogs were used and their mandibular and maxilar premolars and molars (PM3; PM4 ; M1 ; PM4 ; M1 ) of both sides were submitted to...
| Κύριοι συγγραφείς: | , , , , , |
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| Μορφή: | Άρθρο |
| Γλώσσα: | English |
| Έκδοση: |
Universidade Estadual de Campinas
2016-01-01
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| Σειρά: | Brazilian Journal of Oral Sciences |
| Θέματα: | |
| Διαθέσιμο Online: | https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8642999 |
| _version_ | 1831534916655906816 |
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| author | Glaucenira de Barros Bruno Ana Paula Nunes Alves Valdenice Aparecida Menezes Maria Cristina Germano Maia José Afonso Bruno Glauce Socorro de Barros Viana |
| author_facet | Glaucenira de Barros Bruno Ana Paula Nunes Alves Valdenice Aparecida Menezes Maria Cristina Germano Maia José Afonso Bruno Glauce Socorro de Barros Viana |
| author_sort | Glaucenira de Barros Bruno |
| collection | DOAJ |
| description | The purpose of this study was to evaluate by histological analysis, the biocompatibility of an antibiotic paste following treatment of pulpotomies in dogs. Four male adult dogs were used and their mandibular and maxilar premolars and molars (PM3; PM4 ; M1 ; PM4 ; M1 ) of both sides were submitted to pulpotomies. The antibiotic paste (CTZ) was prepared with chloramphenicol, tetracycline, zinc oxide and eugenol. After 6, 8, 9 and 10 months post-pulpotomy the dogs were sacrificed. Histological analysis of the teeth revealed an intense inflammatory process in the coronal pulp at 6 months after pulpotomy, with inflammatory cells dispersed throughout the entire apical region in this period. This process became partially reduced at 8 and 9 months after pulpotomy, and totally disappeared by the end of the experiment, at 10 months. In conclusion, the endodontic treatment with this antibiotic paste seemed to be biocompatible under the present experimental conditions. However, further clinical studies are necessary to assure that this paste is safe for use in pulpotomies in children. |
| first_indexed | 2024-12-16T22:24:50Z |
| format | Article |
| id | doaj.art-afbc2d2661f34efb8ba6d9f8416e614d |
| institution | Directory Open Access Journal |
| issn | 1677-3225 |
| language | English |
| last_indexed | 2024-12-16T22:24:50Z |
| publishDate | 2016-01-01 |
| publisher | Universidade Estadual de Campinas |
| record_format | Article |
| series | Brazilian Journal of Oral Sciences |
| spelling | doaj.art-afbc2d2661f34efb8ba6d9f8416e614d2022-12-21T22:13:55ZengUniversidade Estadual de CampinasBrazilian Journal of Oral Sciences1677-32252016-01-0162210.20396/bjos.v6i22.8642999Biocompatibility evaluation of an antibiotic paste after pulpotomy in dogsGlaucenira de Barros Bruno0Ana Paula Nunes Alves1Valdenice Aparecida Menezes2Maria Cristina Germano Maia3José Afonso Bruno4Glauce Socorro de Barros Viana5Federal University of CearáFederal University of CearáPernambuco State UniversityUniversity of FortalezaFaculty of Medicine of Juazeiro do NorteFaculty of Medicine of Juazeiro do NorteThe purpose of this study was to evaluate by histological analysis, the biocompatibility of an antibiotic paste following treatment of pulpotomies in dogs. Four male adult dogs were used and their mandibular and maxilar premolars and molars (PM3; PM4 ; M1 ; PM4 ; M1 ) of both sides were submitted to pulpotomies. The antibiotic paste (CTZ) was prepared with chloramphenicol, tetracycline, zinc oxide and eugenol. After 6, 8, 9 and 10 months post-pulpotomy the dogs were sacrificed. Histological analysis of the teeth revealed an intense inflammatory process in the coronal pulp at 6 months after pulpotomy, with inflammatory cells dispersed throughout the entire apical region in this period. This process became partially reduced at 8 and 9 months after pulpotomy, and totally disappeared by the end of the experiment, at 10 months. In conclusion, the endodontic treatment with this antibiotic paste seemed to be biocompatible under the present experimental conditions. However, further clinical studies are necessary to assure that this paste is safe for use in pulpotomies in children.https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8642999Pulp therapy. Pulpotomy. Antibiotic paste. Biocompatibility tests |
| spellingShingle | Glaucenira de Barros Bruno Ana Paula Nunes Alves Valdenice Aparecida Menezes Maria Cristina Germano Maia José Afonso Bruno Glauce Socorro de Barros Viana Biocompatibility evaluation of an antibiotic paste after pulpotomy in dogs Brazilian Journal of Oral Sciences Pulp therapy. Pulpotomy. Antibiotic paste. Biocompatibility tests |
| title | Biocompatibility evaluation of an antibiotic paste after pulpotomy in dogs |
| title_full | Biocompatibility evaluation of an antibiotic paste after pulpotomy in dogs |
| title_fullStr | Biocompatibility evaluation of an antibiotic paste after pulpotomy in dogs |
| title_full_unstemmed | Biocompatibility evaluation of an antibiotic paste after pulpotomy in dogs |
| title_short | Biocompatibility evaluation of an antibiotic paste after pulpotomy in dogs |
| title_sort | biocompatibility evaluation of an antibiotic paste after pulpotomy in dogs |
| topic | Pulp therapy. Pulpotomy. Antibiotic paste. Biocompatibility tests |
| url | https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8642999 |
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