Preoperative prediction of cholangiocyte phenotype hepatocellular carcinoma on contrast-enhanced MRI and the prognostic implication after hepatectomy

Preoperative prediction of cholangiocyte phenotype hepatocellular carcinoma on contrast-enhanced MRI and the prognostic implication after hepatectomy

Abstract Background Hepatocellular carcinoma (HCC) expressing cytokeratin (CK) 7 or CK19 has a cholangiocyte phenotype that stimulates HCC proliferation, metastasis, and sorafenib therapy resistance This study aims to noninvasively predict cholangiocyte phenotype-positive HCC and assess its prognosi...

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Bibliographic Details
Main Authors: Yidi Chen, Jie Chen, Chongtu Yang, Yuanan Wu, Hong Wei, Ting Duan, Zhen Zhang, Liling Long, Hanyu Jiang, Bin Song
Format: Article
Language:English
Published: SpringerOpen 2023-11-01
Series:Insights into Imaging
Subjects:
Hepatocellular carcinoma
Magnetic resonance imaging
Cytokeratin 7
Cytokeratin 19
Cholangiocyte phenotype
Online Access:https://doi.org/10.1186/s13244-023-01539-x

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