Intestinal manifestations of Behçet's disease
Behçet's disease (BD) is a systemic vasculitis of unknown origin, characterized by recurrences of the ulcerative process in the oral cavity and on the genitals, inflammatory damage of the eyes, joints, vessels and other organs. The severity and prognosis of BD determines organ pathology. Intest...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
"Consilium Medicum" Publishing house
2019-05-01
|
| Series: | Терапевтический архив |
| Subjects: | |
| Online Access: | https://ter-arkhiv.ru/0040-3660/article/viewFile/33648/pdf |
| _version_ | 1819263060032880640 |
|---|---|
| author | R G Goloeva Z S Alekberova T A Lisitsyna E A Stepanova L P Orlova |
| author_facet | R G Goloeva Z S Alekberova T A Lisitsyna E A Stepanova L P Orlova |
| author_sort | R G Goloeva |
| collection | DOAJ |
| description | Behçet's disease (BD) is a systemic vasculitis of unknown origin, characterized by recurrences of the ulcerative process in the oral cavity and on the genitals, inflammatory damage of the eyes, joints, vessels and other organs. The severity and prognosis of BD determines organ pathology. Intestinal manifestations of BD (intestinal BD) are the least studied. Its verification in BD is complicated by the variety of clinical manifestations, their similarity with inflammatory bowel diseases, the lack of informative laboratory tests, pathognomonic endoscopic and histological signs. Intestinal BD can lead to serious complications (massive bleeding, intestinal perforation and fistula formation), which can not only significantly reduce the quality of the patient’s life, but also cause death. Treatment of intestinal BD is not standardized; it is mainly empirical and conducted courses. The purpose of therapy is to achieve clinical remission, healing of intestinal ulcers and prevention of surgery. The article presents a case of severe refractory intestinal BD, requiring twice emergency surgical care - removal of half and then the whole of the colon because of multiple perforations. A brief review of the literature is given and diagnostic difficulties of intestinal BD are discussed. |
| first_indexed | 2024-12-23T20:07:35Z |
| format | Article |
| id | doaj.art-afc0d4df9a6e4a5a8eee294387abcf3e |
| institution | Directory Open Access Journal |
| issn | 0040-3660 2309-5342 |
| language | Russian |
| last_indexed | 2024-12-23T20:07:35Z |
| publishDate | 2019-05-01 |
| publisher | "Consilium Medicum" Publishing house |
| record_format | Article |
| series | Терапевтический архив |
| spelling | doaj.art-afc0d4df9a6e4a5a8eee294387abcf3e2022-12-21T17:32:54Zrus"Consilium Medicum" Publishing houseТерапевтический архив0040-36602309-53422019-05-0191511111910.26442/00403660.2019.05.00024730378Intestinal manifestations of Behçet's diseaseR G Goloeva0Z S Alekberova1T A Lisitsyna2E A Stepanova3L P Orlova4V.A. Nasonova Scientific and Research Institute of RheumatologyV.A. Nasonova Scientific and Research Institute of RheumatologyV.A. Nasonova Scientific and Research Institute of RheumatologyV.M. Buyanova Municipal clinical hospitalA.N. Ryzhikh State Scientific Centre of ColoproctologyBehçet's disease (BD) is a systemic vasculitis of unknown origin, characterized by recurrences of the ulcerative process in the oral cavity and on the genitals, inflammatory damage of the eyes, joints, vessels and other organs. The severity and prognosis of BD determines organ pathology. Intestinal manifestations of BD (intestinal BD) are the least studied. Its verification in BD is complicated by the variety of clinical manifestations, their similarity with inflammatory bowel diseases, the lack of informative laboratory tests, pathognomonic endoscopic and histological signs. Intestinal BD can lead to serious complications (massive bleeding, intestinal perforation and fistula formation), which can not only significantly reduce the quality of the patient’s life, but also cause death. Treatment of intestinal BD is not standardized; it is mainly empirical and conducted courses. The purpose of therapy is to achieve clinical remission, healing of intestinal ulcers and prevention of surgery. The article presents a case of severe refractory intestinal BD, requiring twice emergency surgical care - removal of half and then the whole of the colon because of multiple perforations. A brief review of the literature is given and diagnostic difficulties of intestinal BD are discussed.https://ter-arkhiv.ru/0040-3660/article/viewFile/33648/pdfbehçet's diseaseintestinal ulcersintestinal perforationcolon-oscopyintestinal ultrasoundhemicolectomy |
| spellingShingle | R G Goloeva Z S Alekberova T A Lisitsyna E A Stepanova L P Orlova Intestinal manifestations of Behçet's disease Терапевтический архив behçet's disease intestinal ulcers intestinal perforation colon-oscopy intestinal ultrasound hemicolectomy |
| title | Intestinal manifestations of Behçet's disease |
| title_full | Intestinal manifestations of Behçet's disease |
| title_fullStr | Intestinal manifestations of Behçet's disease |
| title_full_unstemmed | Intestinal manifestations of Behçet's disease |
| title_short | Intestinal manifestations of Behçet's disease |
| title_sort | intestinal manifestations of behcet s disease |
| topic | behçet's disease intestinal ulcers intestinal perforation colon-oscopy intestinal ultrasound hemicolectomy |
| url | https://ter-arkhiv.ru/0040-3660/article/viewFile/33648/pdf |
| work_keys_str_mv | AT rggoloeva intestinalmanifestationsofbehcetsdisease AT zsalekberova intestinalmanifestationsofbehcetsdisease AT talisitsyna intestinalmanifestationsofbehcetsdisease AT eastepanova intestinalmanifestationsofbehcetsdisease AT lporlova intestinalmanifestationsofbehcetsdisease |