Branched actin networks are organized for asymmetric force production during clathrin-mediated endocytosis in mammalian cells

Drubin et al. use three different advanced imaging approaches to show that actin assembles preferentially at stalled clathrin-mediated endocytosis sites, where the actin pulls vesicles into the cell asymmetrically, as a bottle opener pulls off a cap.

Bibliographic Details
Main Authors: Meiyan Jin, Cyna Shirazinejad, Bowen Wang, Amy Yan, Johannes Schöneberg, Srigokul Upadhyayula, Ke Xu, David G. Drubin
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-31207-5