Acute permethrin neurotoxicity: Variable presentations, high index of suspicion
Permethrin is a synthetic Type I pyrethroidal neurotoxic pesticide that has been responsible for accidental animal deaths. Despite its widespread use, there are no published case reports on pediatric intensive care unit admissions due to permethrin exposure. We report the unusual and varied presenta...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2014-01-01
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| Series: | Toxicology Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214750014000882 |
| _version_ | 1811196597466300416 |
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| author | Bonny Drago Namrata S. Shah Samir H. Shah |
| author_facet | Bonny Drago Namrata S. Shah Samir H. Shah |
| author_sort | Bonny Drago |
| collection | DOAJ |
| description | Permethrin is a synthetic Type I pyrethroidal neurotoxic pesticide that has been responsible for accidental animal deaths. Despite its widespread use, there are no published case reports on pediatric intensive care unit admissions due to permethrin exposure. We report the unusual and varied presentations of permethrin toxicity in three siblings presenting to a tertiary care pediatric intensive care unit (PICU). While there is no standard clinical diagnostic test for permethrin, accurate diagnosis was obtained by rapidly analyzing the offending agent. In the absence of a known antidote for permethrin, supportive management was initiated and resulted in a favorable outcome for all three siblings. |
| first_indexed | 2024-04-12T01:00:21Z |
| format | Article |
| id | doaj.art-afc6532a14bd4b3185909e3277188c96 |
| institution | Directory Open Access Journal |
| issn | 2214-7500 |
| language | English |
| last_indexed | 2024-04-12T01:00:21Z |
| publishDate | 2014-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Toxicology Reports |
| spelling | doaj.art-afc6532a14bd4b3185909e3277188c962022-12-22T03:54:28ZengElsevierToxicology Reports2214-75002014-01-011C1026102810.1016/j.toxrep.2014.09.007Acute permethrin neurotoxicity: Variable presentations, high index of suspicionBonny Drago0Namrata S. Shah1Samir H. Shah2Department of Pediatrics, State University of New York at Stony Brook, New York, NY 11790, USADepartment of Pediatric Neurology, Le Bonheur Children's Hospital and The University of Tennessee Health Science Center, Memphis, TN 38103, USADepartment of Pediatric Critical Care Medicine, Le Bonheur Children's Hospital and The University of Tennessee Health Science Center, Memphis, TN 38103, USAPermethrin is a synthetic Type I pyrethroidal neurotoxic pesticide that has been responsible for accidental animal deaths. Despite its widespread use, there are no published case reports on pediatric intensive care unit admissions due to permethrin exposure. We report the unusual and varied presentations of permethrin toxicity in three siblings presenting to a tertiary care pediatric intensive care unit (PICU). While there is no standard clinical diagnostic test for permethrin, accurate diagnosis was obtained by rapidly analyzing the offending agent. In the absence of a known antidote for permethrin, supportive management was initiated and resulted in a favorable outcome for all three siblings.http://www.sciencedirect.com/science/article/pii/S2214750014000882PermethrinToxicologyNeurological presentations |
| spellingShingle | Bonny Drago Namrata S. Shah Samir H. Shah Acute permethrin neurotoxicity: Variable presentations, high index of suspicion Toxicology Reports Permethrin Toxicology Neurological presentations |
| title | Acute permethrin neurotoxicity: Variable presentations, high index of suspicion |
| title_full | Acute permethrin neurotoxicity: Variable presentations, high index of suspicion |
| title_fullStr | Acute permethrin neurotoxicity: Variable presentations, high index of suspicion |
| title_full_unstemmed | Acute permethrin neurotoxicity: Variable presentations, high index of suspicion |
| title_short | Acute permethrin neurotoxicity: Variable presentations, high index of suspicion |
| title_sort | acute permethrin neurotoxicity variable presentations high index of suspicion |
| topic | Permethrin Toxicology Neurological presentations |
| url | http://www.sciencedirect.com/science/article/pii/S2214750014000882 |
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