The Formin mDia1 Regulates Acute Lymphoblastic Leukemia Engraftment, Migration, and Progression in vivo
Leukemias typically arise in the bone marrow and then spread to the blood and into other tissues. To disseminate into tissues, leukemia cells migrate into the blood stream and then exit the circulation by migrating across vascular endothelial barriers. Formin proteins regulate cytoskeletal remodelin...
Main Authors: | Scott B. Thompson, Eric J. Wigton, Sai Harsha Krovi, Jeffrey W. Chung, Robert A. Long, Jordan Jacobelli |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2018-09-01
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Series: | Frontiers in Oncology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fonc.2018.00389/full |
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