Radiopharmaceuticals for diagnosis in nuclear medicine: a short review
Radiopharmaceuticals are radioactive compounds which have a bound radionuclide in their structure, whose purpose is directing the radionuclide to a location to be treated or to obtain images. Nuclear medicine is the medical specialty that employs radiopharmaceuticals, which has presented itself as a...
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| Format: | Article |
| Language: | English |
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Universidade Estadual Paulista
2019-07-01
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| Series: | Eclética Química |
| Online Access: | https://revista.iq.unesp.br/ojs/index.php/ecletica/article/view/1032 |
| _version_ | 1818307429292572672 |
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| author | Filipe Boccato Payolla Antonio Carlos Massabni Chris Orvig |
| author_facet | Filipe Boccato Payolla Antonio Carlos Massabni Chris Orvig |
| author_sort | Filipe Boccato Payolla |
| collection | DOAJ |
| description | Radiopharmaceuticals are radioactive compounds which have a bound radionuclide in their structure, whose purpose is directing the radionuclide to a location to be treated or to obtain images. Nuclear medicine is the medical specialty that employs radiopharmaceuticals, which has presented itself as a tremendously useful ally for medicine assisting in various diagnoses and treatments, especially for cancer. The general objective of this work is to identify the main radionuclides and metal complexes currently used as radiopharmaceuticals. The main metal complexes used as radiopharmaceuticals are compounds of technetium (99mTc) like sodium pertechnetate and methylenediphosphonate MDP-99mTc and other compounds of indium (111In), thallium (201Tl), gallium (67Ga, 68Ga), iodine (123I and 131I), chromium (51Cr), sulphur (35S), phosphorus (32P), fluorine (as fluorodeoxyglucose, 18F-FDG and sodium fluorine, Na18F), which are widely used in the nuclear medicine for diagnosis by imaging. They have been of great importance for the early diagnosis of numerous diseases, mainly cancer.Currently, technetium compounds are the majority of radiopharmaceuticals used in all countries. In Brazil, Institute of Energy and Nuclear Research (IPEN) is one of the most important distributors of radiopharmaceuticals, producing, importing and distributing them to clinics and hospitals over the country. |
| first_indexed | 2024-12-13T06:58:14Z |
| format | Article |
| id | doaj.art-afcc1ae76c9544f6903bfb09e9817e2d |
| institution | Directory Open Access Journal |
| issn | 1678-4618 |
| language | English |
| last_indexed | 2024-12-13T06:58:14Z |
| publishDate | 2019-07-01 |
| publisher | Universidade Estadual Paulista |
| record_format | Article |
| series | Eclética Química |
| spelling | doaj.art-afcc1ae76c9544f6903bfb09e9817e2d2022-12-21T23:56:00ZengUniversidade Estadual PaulistaEclética Química1678-46182019-07-01443111910.26850/1678-4618eqj.v44.3.2019.p11-191032Radiopharmaceuticals for diagnosis in nuclear medicine: a short reviewFilipe Boccato Payolla0Antonio Carlos Massabni1Chris Orvig2University of Araraquara (Uniara), 1217 Carlos Gomes St., Araraquara, São Paulo, BrazilInstitute of Chemistry Unesp Araraquara (Unesp); University of Araraquara (Uniara)Medicinal Inorganic Chemistry Group, University of British Columbia, 2036 Main Mall, Vancouver, British Columbia V6T 1Z1Radiopharmaceuticals are radioactive compounds which have a bound radionuclide in their structure, whose purpose is directing the radionuclide to a location to be treated or to obtain images. Nuclear medicine is the medical specialty that employs radiopharmaceuticals, which has presented itself as a tremendously useful ally for medicine assisting in various diagnoses and treatments, especially for cancer. The general objective of this work is to identify the main radionuclides and metal complexes currently used as radiopharmaceuticals. The main metal complexes used as radiopharmaceuticals are compounds of technetium (99mTc) like sodium pertechnetate and methylenediphosphonate MDP-99mTc and other compounds of indium (111In), thallium (201Tl), gallium (67Ga, 68Ga), iodine (123I and 131I), chromium (51Cr), sulphur (35S), phosphorus (32P), fluorine (as fluorodeoxyglucose, 18F-FDG and sodium fluorine, Na18F), which are widely used in the nuclear medicine for diagnosis by imaging. They have been of great importance for the early diagnosis of numerous diseases, mainly cancer.Currently, technetium compounds are the majority of radiopharmaceuticals used in all countries. In Brazil, Institute of Energy and Nuclear Research (IPEN) is one of the most important distributors of radiopharmaceuticals, producing, importing and distributing them to clinics and hospitals over the country.https://revista.iq.unesp.br/ojs/index.php/ecletica/article/view/1032 |
| spellingShingle | Filipe Boccato Payolla Antonio Carlos Massabni Chris Orvig Radiopharmaceuticals for diagnosis in nuclear medicine: a short review Eclética Química |
| title | Radiopharmaceuticals for diagnosis in nuclear medicine: a short review |
| title_full | Radiopharmaceuticals for diagnosis in nuclear medicine: a short review |
| title_fullStr | Radiopharmaceuticals for diagnosis in nuclear medicine: a short review |
| title_full_unstemmed | Radiopharmaceuticals for diagnosis in nuclear medicine: a short review |
| title_short | Radiopharmaceuticals for diagnosis in nuclear medicine: a short review |
| title_sort | radiopharmaceuticals for diagnosis in nuclear medicine a short review |
| url | https://revista.iq.unesp.br/ojs/index.php/ecletica/article/view/1032 |
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