Genetically Proxied Inhibition of Coagulation Factors and Risk of Cardiovascular Disease: A Mendelian Randomization Study

Genetically Proxied Inhibition of Coagulation Factors and Risk of Cardiovascular Disease: A Mendelian Randomization Study

Background We conducted Mendelian randomization analyses investigating the linear associations of genetically proxied inhibition of different coagulation factors with risk of common cardiovascular diseases. Methods and Results Genetic instruments proxying coagulation factor inhibition were identifie...

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Bibliographic Details
Main Authors: Shuai Yuan, Stephen Burgess, Mike Laffan, Amy M. Mason, Martin Dichgans, Dipender Gill, Susanna C. Larsson
Format: Article
Language:English
Published: Wiley 2021-04-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
cardiovascular disease
coagulation
Mendelian randomization analysis
stroke
venous thromboembolism
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.120.019644

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