Fibroblast Growth Factor Type 1 Ameliorates High-Glucose-Induced Oxidative Stress and Neuroinflammation in Retinal Pigment Epithelial Cells and a Streptozotocin-Induced Diabetic Rat Model

Fibroblast Growth Factor Type 1 Ameliorates High-Glucose-Induced Oxidative Stress and Neuroinflammation in Retinal Pigment Epithelial Cells and a Streptozotocin-Induced Diabetic Rat Model

Diabetic retinopathy (DR) is a common complication of diabetes that causes severe visual impairment globally. The pathogenesis of DR is related to oxidative stress and chronic inflammation. The fibroblast growth factor type 1 (FGF-1) mitogen plays crucial roles in cell function, development, and met...

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Bibliographic Details
Main Authors: Hsin-Wei Huang, Chung-May Yang, Chang-Hao Yang
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
fibroblast growth factor type 1
diabetic retinopathy
oxidative stress
inflammatory mediator
p38 mitogen-activated kinase
nuclear factor-κB
Online Access:https://www.mdpi.com/1422-0067/22/13/7233

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https://www.mdpi.com/1422-0067/22/13/7233

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