The Potential of Targeting Brain Pathology with Ascl1/Mash1
The proneural factor Achaete-scute complex-like 1 (Ascl1/Mash1) acts as a pioneering transcription factor that initializes neuronal reprogramming. It drives neural progenitors and non-neuronal cells to exit the cell cycle, and promotes neuronal differentiation by activating neuronal target genes, ev...
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| Format: | Article |
| Language: | English |
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MDPI AG
2017-08-01
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| Series: | Cells |
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| Online Access: | https://www.mdpi.com/2073-4409/6/3/26 |