Transient total blindness associated with alcoholic ketoacidosis

Background Methanol poisoning is often suspected in patients with high anion gap metabolic acidosis and visual deficits. Although alcoholic ketoacidosis can cause high anion gap metabolic acidosis, reports on vision loss are limited. We report the case of a patient with alcoholic ketoacidosis with t...

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Main Authors: Hiroki Sato, Ryoko Kyan, Chinami Kamada, Mitsunori Kaku, Shota Sato, Toshihiro Tawara, Eiji Sakawaki, Sonoko Sakawaki, Yoshihiro Takeyama
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Acute Medicine & Surgery
Subjects:
Online Access:https://doi.org/10.1002/ams2.660
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author Hiroki Sato
Ryoko Kyan
Chinami Kamada
Mitsunori Kaku
Shota Sato
Toshihiro Tawara
Eiji Sakawaki
Sonoko Sakawaki
Yoshihiro Takeyama
author_facet Hiroki Sato
Ryoko Kyan
Chinami Kamada
Mitsunori Kaku
Shota Sato
Toshihiro Tawara
Eiji Sakawaki
Sonoko Sakawaki
Yoshihiro Takeyama
author_sort Hiroki Sato
collection DOAJ
description Background Methanol poisoning is often suspected in patients with high anion gap metabolic acidosis and visual deficits. Although alcoholic ketoacidosis can cause high anion gap metabolic acidosis, reports on vision loss are limited. We report the case of a patient with alcoholic ketoacidosis with transient total blindness. Case Presentation A 56‐year‐old man complaining of total blindness was transferred to our hospital. Physical examination revealed a clear consciousness and mydriasis with an absence of pupillary light reflex. Blood analysis revealed high anion gap metabolic acidosis with a high ketone body concentration. Alcoholic ketoacidosis was diagnosed because the patient had a chronic alcohol abuse history and denied methanol intake. As acidemia improved because of fluid infusion and glucose and vitamin B1 supplementation, his visual acuity recovered. He was discharged after 44 days without visual deficits. Conclusion Patients with alcoholic ketoacidosis may present with acute vision loss, which recovers along with treatment.
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spelling doaj.art-afd16c212ef340ac82c0f405fbb7bd5e2022-12-21T18:12:35ZengWileyAcute Medicine & Surgery2052-88172021-01-0181n/an/a10.1002/ams2.660Transient total blindness associated with alcoholic ketoacidosisHiroki Sato0Ryoko Kyan1Chinami Kamada2Mitsunori Kaku3Shota Sato4Toshihiro Tawara5Eiji Sakawaki6Sonoko Sakawaki7Yoshihiro Takeyama8Department of Emergency Medicine Hakodate Municipal Hospital Hakodate JapanClinical Toxicology Center Saitama Medical University Hospital Saitama JapanDepartment of Emergency Medicine Hakodate Municipal Hospital Hakodate JapanDepartment of Emergency Medicine Hakodate Municipal Hospital Hakodate JapanDepartment of Emergency Medicine Hakodate Municipal Hospital Hakodate JapanDepartment of Emergency Medicine Hakodate Municipal Hospital Hakodate JapanDepartment of Emergency Medicine Hakodate Municipal Hospital Hakodate JapanDepartment of Emergency Medicine Hakodate Municipal Hospital Hakodate JapanDepartment of Emergency Medicine Hakodate Municipal Hospital Hakodate JapanBackground Methanol poisoning is often suspected in patients with high anion gap metabolic acidosis and visual deficits. Although alcoholic ketoacidosis can cause high anion gap metabolic acidosis, reports on vision loss are limited. We report the case of a patient with alcoholic ketoacidosis with transient total blindness. Case Presentation A 56‐year‐old man complaining of total blindness was transferred to our hospital. Physical examination revealed a clear consciousness and mydriasis with an absence of pupillary light reflex. Blood analysis revealed high anion gap metabolic acidosis with a high ketone body concentration. Alcoholic ketoacidosis was diagnosed because the patient had a chronic alcohol abuse history and denied methanol intake. As acidemia improved because of fluid infusion and glucose and vitamin B1 supplementation, his visual acuity recovered. He was discharged after 44 days without visual deficits. Conclusion Patients with alcoholic ketoacidosis may present with acute vision loss, which recovers along with treatment.https://doi.org/10.1002/ams2.660Alcohol abusealcoholic ketoacidosistoxicology/poisoningtransient blindnessvision loss
spellingShingle Hiroki Sato
Ryoko Kyan
Chinami Kamada
Mitsunori Kaku
Shota Sato
Toshihiro Tawara
Eiji Sakawaki
Sonoko Sakawaki
Yoshihiro Takeyama
Transient total blindness associated with alcoholic ketoacidosis
Acute Medicine & Surgery
Alcohol abuse
alcoholic ketoacidosis
toxicology/poisoning
transient blindness
vision loss
title Transient total blindness associated with alcoholic ketoacidosis
title_full Transient total blindness associated with alcoholic ketoacidosis
title_fullStr Transient total blindness associated with alcoholic ketoacidosis
title_full_unstemmed Transient total blindness associated with alcoholic ketoacidosis
title_short Transient total blindness associated with alcoholic ketoacidosis
title_sort transient total blindness associated with alcoholic ketoacidosis
topic Alcohol abuse
alcoholic ketoacidosis
toxicology/poisoning
transient blindness
vision loss
url https://doi.org/10.1002/ams2.660
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AT mitsunorikaku transienttotalblindnessassociatedwithalcoholicketoacidosis
AT shotasato transienttotalblindnessassociatedwithalcoholicketoacidosis
AT toshihirotawara transienttotalblindnessassociatedwithalcoholicketoacidosis
AT eijisakawaki transienttotalblindnessassociatedwithalcoholicketoacidosis
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