Preparation and Characterization of Novel Pharmaceutical Co-Crystals: Ticagrelor with Nicotinamide

Preparation and Characterization of Novel Pharmaceutical Co-Crystals: Ticagrelor with Nicotinamide

Two new co-crystals, Ticagrelor with Nicotinamide, have been prepared with improved solubility. Because Ticalegor has a poor solubility and dissolution rate, a novel co-crystallization method with structurally homogenous crystalline material, an active pharmaceutical ingredient (API), and co-former...

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Bibliographic Details
Main Authors: Muhammad Inam, Jiajia Wu, Jie Shen, Chi Uyen Phan, Guping Tang, Xiurong Hu
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Crystals
Subjects:
co-crystal
ticagrelor
nicotinamide
solubility
dissolution
Online Access:http://www.mdpi.com/2073-4352/8/9/336

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