Role of real-world evidence studies in cardiology
The introduction of evidence-based medicine into practical healthcare provides physicians with the opportunity to use treatment approaches, which have been proven to be effective in randomized controlled trials. In this case, it is necessary to consider using the medication in a particular patient i...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
«FIRMA «SILICEA» LLC
2021-10-01
|
| Series: | Российский кардиологический журнал |
| Subjects: | |
| Online Access: | https://russjcardiol.elpub.ru/jour/article/view/4636 |
| _version_ | 1826561071525134336 |
|---|---|
| author | T. V. Pavlova |
| author_facet | T. V. Pavlova |
| author_sort | T. V. Pavlova |
| collection | DOAJ |
| description | The introduction of evidence-based medicine into practical healthcare provides physicians with the opportunity to use treatment approaches, which have been proven to be effective in randomized controlled trials. In this case, it is necessary to consider using the medication in a particular patient in accordance with the design of clinical trials and strictly follow the instructions. Drugs should be critically selected with focus on quality of available efficacy and safety data obtained in the population closest to a patient. In addition, clinicians should regularly review the available data with particular regard to its quality. The advantages, disadvantages, limitations and methodological problems of observational studies should be carefully considered during the interpretation of results. At the same time, the compliance of the results of real-world evidence studies with registration trial data indicates a high reproducibility of medication effects. |
| first_indexed | 2024-04-09T20:44:50Z |
| format | Article |
| id | doaj.art-afd8b37727694e9688404e79dd5863d1 |
| institution | Directory Open Access Journal |
| issn | 1560-4071 2618-7620 |
| language | Russian |
| last_indexed | 2025-03-14T09:26:21Z |
| publishDate | 2021-10-01 |
| publisher | «FIRMA «SILICEA» LLC |
| record_format | Article |
| series | Российский кардиологический журнал |
| spelling | doaj.art-afd8b37727694e9688404e79dd5863d12025-03-02T11:42:56Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202021-10-01263S10.15829/1560-4071-2021-46363361Role of real-world evidence studies in cardiologyT. V. Pavlova0Samara State Medical UniversityThe introduction of evidence-based medicine into practical healthcare provides physicians with the opportunity to use treatment approaches, which have been proven to be effective in randomized controlled trials. In this case, it is necessary to consider using the medication in a particular patient in accordance with the design of clinical trials and strictly follow the instructions. Drugs should be critically selected with focus on quality of available efficacy and safety data obtained in the population closest to a patient. In addition, clinicians should regularly review the available data with particular regard to its quality. The advantages, disadvantages, limitations and methodological problems of observational studies should be carefully considered during the interpretation of results. At the same time, the compliance of the results of real-world evidence studies with registration trial data indicates a high reproducibility of medication effects.https://russjcardiol.elpub.ru/jour/article/view/4636clinical trialsroutine clinical practicedirect oral anticoagulants |
| spellingShingle | T. V. Pavlova Role of real-world evidence studies in cardiology Российский кардиологический журнал clinical trials routine clinical practice direct oral anticoagulants |
| title | Role of real-world evidence studies in cardiology |
| title_full | Role of real-world evidence studies in cardiology |
| title_fullStr | Role of real-world evidence studies in cardiology |
| title_full_unstemmed | Role of real-world evidence studies in cardiology |
| title_short | Role of real-world evidence studies in cardiology |
| title_sort | role of real world evidence studies in cardiology |
| topic | clinical trials routine clinical practice direct oral anticoagulants |
| url | https://russjcardiol.elpub.ru/jour/article/view/4636 |
| work_keys_str_mv | AT tvpavlova roleofrealworldevidencestudiesincardiology |