Detection of Phenuiviridae, Chuviridae Members, and a Novel Quaranjavirus in Hard Ticks From Danube Delta
Ticks are involved in the transmission of various pathogens and several tick-borne diseases cause significant problems for the health of humans and livestock. The members of the Quaranjavirus genus are mainly associated with argas ticks but recent studies demonstrated the presence of novel quaranjav...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-04-01
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| Series: | Frontiers in Veterinary Science |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fvets.2022.863814/full |
| _version_ | 1818262205658824704 |
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| author | Bianca Elena Bratuleanu Bianca Elena Bratuleanu Sarah Temmam Sarah Temmam Sandie Munier Delphine Chrétien Delphine Chrétien Thomas Bigot Sylvie van der Werf Sylvie van der Werf Gheorghe Savuta Marc Eloit Marc Eloit Marc Eloit |
| author_facet | Bianca Elena Bratuleanu Bianca Elena Bratuleanu Sarah Temmam Sarah Temmam Sandie Munier Delphine Chrétien Delphine Chrétien Thomas Bigot Sylvie van der Werf Sylvie van der Werf Gheorghe Savuta Marc Eloit Marc Eloit Marc Eloit |
| author_sort | Bianca Elena Bratuleanu |
| collection | DOAJ |
| description | Ticks are involved in the transmission of various pathogens and several tick-borne diseases cause significant problems for the health of humans and livestock. The members of the Quaranjavirus genus are mainly associated with argas ticks but recent studies demonstrated the presence of novel quaranjaviruses-like in ixodid ticks. In 2020, 169 Rhipicephalus sanguineus ticks were collected in Southern Romania from small ruminants and analyzed by high-throughput transcriptome sequencing. Among the viral families that infect Romanian ticks, we have identified sequences from Phenuiviridae (Brown dog tick phlebovirus 1 [BDTPV1] and Brown dog tick phlebovirus 2 [BDTPV2]) and Chuviridae families (Cataloi mivirus [CTMV]), and numerous sequences from a new quaranjavirus-like, tentatively named Cataloi tick quaranjavirus (CTQV). Phylogenetic analyses performed on the five segments show that CTQV is phylogenetically positioned within a clade that encompasses Ixodidae-borne viruses associated with iguanas, small ruminants, seabirds, and penguins distributed across different geographical areas. Furthermore, CTQV is positioned differently depending on the segment considered. This is the first report on the detection of a quaranjavirus-like in Eastern Europe. Further investigations are needed to discern its infectivity and pathogenicity against vertebrates. |
| first_indexed | 2024-12-12T18:59:26Z |
| format | Article |
| id | doaj.art-afda7e83b64a4e95a2de2946ccf0dfa3 |
| institution | Directory Open Access Journal |
| issn | 2297-1769 |
| language | English |
| last_indexed | 2024-12-12T18:59:26Z |
| publishDate | 2022-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Veterinary Science |
| spelling | doaj.art-afda7e83b64a4e95a2de2946ccf0dfa32022-12-22T00:15:07ZengFrontiers Media S.A.Frontiers in Veterinary Science2297-17692022-04-01910.3389/fvets.2022.863814863814Detection of Phenuiviridae, Chuviridae Members, and a Novel Quaranjavirus in Hard Ticks From Danube DeltaBianca Elena Bratuleanu0Bianca Elena Bratuleanu1Sarah Temmam2Sarah Temmam3Sandie Munier4Delphine Chrétien5Delphine Chrétien6Thomas Bigot7Sylvie van der Werf8Sylvie van der Werf9Gheorghe Savuta10Marc Eloit11Marc Eloit12Marc Eloit13Pathogen Discovery Laboratory, Institut Pasteur, Paris, FranceRegional Center of Advanced Research for Emerging Diseases, Zoonoses and Food Safety (ROVETEMERG), “Ion Ionescu de la Brad”, University of Life Sciences, Iasi, RomaniaPathogen Discovery Laboratory, Institut Pasteur, Paris, FranceInstitut Pasteur, OIE Collaborating Centre for Detection and Identification in Humans of Emerging Animal Pathogens, Paris, FranceInstitut Pasteur, Molecular Genetics of RNA Viruses Unit, CNRS UMR 3569, Université de Paris, Paris, FrancePathogen Discovery Laboratory, Institut Pasteur, Paris, FranceInstitut Pasteur, OIE Collaborating Centre for Detection and Identification in Humans of Emerging Animal Pathogens, Paris, FrancePathogen Discovery Laboratory, Institut Pasteur, Paris, FranceInstitut Pasteur, Molecular Genetics of RNA Viruses Unit, CNRS UMR 3569, Université de Paris, Paris, FranceInstitut Pasteur, National Reference Center for Respiratory Viruses, Paris, FranceRegional Center of Advanced Research for Emerging Diseases, Zoonoses and Food Safety (ROVETEMERG), “Ion Ionescu de la Brad”, University of Life Sciences, Iasi, RomaniaPathogen Discovery Laboratory, Institut Pasteur, Paris, FranceInstitut Pasteur, OIE Collaborating Centre for Detection and Identification in Humans of Emerging Animal Pathogens, Paris, FranceAlfort National Veterinary School, Maisons-Alfort, FranceTicks are involved in the transmission of various pathogens and several tick-borne diseases cause significant problems for the health of humans and livestock. The members of the Quaranjavirus genus are mainly associated with argas ticks but recent studies demonstrated the presence of novel quaranjaviruses-like in ixodid ticks. In 2020, 169 Rhipicephalus sanguineus ticks were collected in Southern Romania from small ruminants and analyzed by high-throughput transcriptome sequencing. Among the viral families that infect Romanian ticks, we have identified sequences from Phenuiviridae (Brown dog tick phlebovirus 1 [BDTPV1] and Brown dog tick phlebovirus 2 [BDTPV2]) and Chuviridae families (Cataloi mivirus [CTMV]), and numerous sequences from a new quaranjavirus-like, tentatively named Cataloi tick quaranjavirus (CTQV). Phylogenetic analyses performed on the five segments show that CTQV is phylogenetically positioned within a clade that encompasses Ixodidae-borne viruses associated with iguanas, small ruminants, seabirds, and penguins distributed across different geographical areas. Furthermore, CTQV is positioned differently depending on the segment considered. This is the first report on the detection of a quaranjavirus-like in Eastern Europe. Further investigations are needed to discern its infectivity and pathogenicity against vertebrates.https://www.frontiersin.org/articles/10.3389/fvets.2022.863814/fullEastern Europenext generation sequencingticksquaranjavirusessmall ruminant |
| spellingShingle | Bianca Elena Bratuleanu Bianca Elena Bratuleanu Sarah Temmam Sarah Temmam Sandie Munier Delphine Chrétien Delphine Chrétien Thomas Bigot Sylvie van der Werf Sylvie van der Werf Gheorghe Savuta Marc Eloit Marc Eloit Marc Eloit Detection of Phenuiviridae, Chuviridae Members, and a Novel Quaranjavirus in Hard Ticks From Danube Delta Frontiers in Veterinary Science Eastern Europe next generation sequencing ticks quaranjaviruses small ruminant |
| title | Detection of Phenuiviridae, Chuviridae Members, and a Novel Quaranjavirus in Hard Ticks From Danube Delta |
| title_full | Detection of Phenuiviridae, Chuviridae Members, and a Novel Quaranjavirus in Hard Ticks From Danube Delta |
| title_fullStr | Detection of Phenuiviridae, Chuviridae Members, and a Novel Quaranjavirus in Hard Ticks From Danube Delta |
| title_full_unstemmed | Detection of Phenuiviridae, Chuviridae Members, and a Novel Quaranjavirus in Hard Ticks From Danube Delta |
| title_short | Detection of Phenuiviridae, Chuviridae Members, and a Novel Quaranjavirus in Hard Ticks From Danube Delta |
| title_sort | detection of phenuiviridae chuviridae members and a novel quaranjavirus in hard ticks from danube delta |
| topic | Eastern Europe next generation sequencing ticks quaranjaviruses small ruminant |
| url | https://www.frontiersin.org/articles/10.3389/fvets.2022.863814/full |
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