Inhibition of Human Cathepsins B and L by Caffeic Acid and Its Derivatives
Caffeic acid (CA) and its derivatives caffeic acid phenethyl ester (CAPE) and chlorogenic acid (CGA) are phenolic compounds of plant origin with a wide range of biological activities. Here, we identify and characterize their inhibitory properties against human cathepsins B and L, potent, ubiquitousl...
Main Authors: | Liza Ulčakar, Marko Novinec |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-12-01
|
Series: | Biomolecules |
Subjects: | |
Online Access: | https://www.mdpi.com/2218-273X/11/1/31 |
Similar Items
-
The Interplay of Glycosaminoglycans and Cysteine Cathepsins in Mucopolysaccharidosis
by: Alexis David, et al.
Published: (2023-03-01) -
Mixed and non-competitive enzyme inhibition: underlying mechanisms and mechanistic irrelevance of the formal two-site model
by: Alessandro Pesaresi
Published: (2023-12-01) -
Inhibition Properties of Some Pyrimidine Derivatives as Anticancer Agents on Glutathione S-Transferase
by: Hatice Esra Duran
Published: (2021-10-01) -
Triterpene Acid and Phenolics from Ancient Apples of Friuli Venezia Giulia as Nutraceutical Ingredients: LC-MS Study and In Vitro Activities
by: Stefania Sut, et al.
Published: (2019-03-01) -
Changes in the Profile of Phenolic Compounds and in the Antioxidant, Hypoglycemic, and Antidiabetic Activities of a Beverage Based on Sesame By-Product Caused by the Simulated Gastrointestinal Digestion Process
by: Jonhatan Carrasco-Chávez, et al.
Published: (2024-11-01)