Ventilation and respiration mechanics in patients with chronic obstructive pulmonary disease in different body positions
The aim of this work was to study changes in mechanical lung properties in cases of COPD in general and in different zones depending on the body position.Materials and methods. The research was performed in 37 patients with chronic obstructive pulmonary disease (COPD) in the vertical and horizontal...
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Siberian State Medical University (Tomsk)
2019-10-01
|
| Series: | Бюллетень сибирской медицины |
| Subjects: | |
| Online Access: | https://bulletin.ssmu.ru/jour/article/view/2397 |
| _version_ | 1797872845036978176 |
|---|---|
| author | Al. Ju. Dish An. Ju. Dish T. S. Ageeva A. L. Karzilov A. V. Teteneva T. P. Kalacheva P. E. Mesko E. L. Mishustina A. A. Zaytseva O. S. Paraeva I. D. Bespalova G. E. Chernogoryuk |
| author_facet | Al. Ju. Dish An. Ju. Dish T. S. Ageeva A. L. Karzilov A. V. Teteneva T. P. Kalacheva P. E. Mesko E. L. Mishustina A. A. Zaytseva O. S. Paraeva I. D. Bespalova G. E. Chernogoryuk |
| author_sort | Al. Ju. Dish |
| collection | DOAJ |
| description | The aim of this work was to study changes in mechanical lung properties in cases of COPD in general and in different zones depending on the body position.Materials and methods. The research was performed in 37 patients with chronic obstructive pulmonary disease (COPD) in the vertical and horizontal positions (VP and HP).Results. The analysis of integral respiration mechanics has revealed a reduction in dynamic lung compliance and an increase in total non-elastic lung resistance during expiration (TNRexp) in HP vs. VP. At the same time, despite the increase in TNRexp in HP, the total work of breathing did not increase. Unlike healthy individuals, the COPD patients were characterized by the absence of differences in regional mechanical properties in both VP and HP. There were no differences in the respiration mechanics of the left lung, and the zones of the right lung only differed in the parameters of regional non-elastic work of breathing (NWBr ) that was increasing from top downwards: the indicators of NWBr during expiration and NWBr in the lower zone were higher as opposed to those of the upper zone in VP. As for HP, NWBr during inspiration, NWBr during expiration and NWBr were higher.Conclusion. The data obtained contradict the prevailing opinion about an escalation in regional differences in ventilation and respiration mechanics under the influence of emerging focal and diffuse inflammatorysclerotic pathological changes in lungs and emphysema. |
| first_indexed | 2024-04-10T01:06:41Z |
| format | Article |
| id | doaj.art-afdb18e38a1540baa452a294feeacca9 |
| institution | Directory Open Access Journal |
| issn | 1682-0363 1819-3684 |
| language | English |
| last_indexed | 2024-04-10T01:06:41Z |
| publishDate | 2019-10-01 |
| publisher | Siberian State Medical University (Tomsk) |
| record_format | Article |
| series | Бюллетень сибирской медицины |
| spelling | doaj.art-afdb18e38a1540baa452a294feeacca92023-03-13T09:58:25ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842019-10-01183374510.20538/1682-0363-2019-3-37-451536Ventilation and respiration mechanics in patients with chronic obstructive pulmonary disease in different body positionsAl. Ju. Dish0An. Ju. Dish1T. S. Ageeva2A. L. Karzilov3A. V. Teteneva4T. P. Kalacheva5P. E. Mesko6E. L. Mishustina7A. A. Zaytseva8O. S. Paraeva9I. D. Bespalova10G. E. Chernogoryuk11Сибирский государственный медицинский университет (СибГМУ)Сибирский государственный медицинский университет (СибГМУ)Сибирский государственный медицинский университет (СибГМУ) 634050, г. Томск, Московский тракт, 2Сибирский государственный медицинский университет (СибГМУ)Медико-санитарная часть № 2; Сибирский государственный медицинский университет (СибГМУ)Сибирский государственный медицинский университет (СибГМУ)Сибирский государственный медицинский университет (СибГМУ)Сибирский государственный медицинский университет (СибГМУ)Сибирский государственный медицинский университет (СибГМУ)Городская больница № 5Сибирский государственный медицинский университет (СибГМУ)Сибирский государственный медицинский университет (СибГМУ)The aim of this work was to study changes in mechanical lung properties in cases of COPD in general and in different zones depending on the body position.Materials and methods. The research was performed in 37 patients with chronic obstructive pulmonary disease (COPD) in the vertical and horizontal positions (VP and HP).Results. The analysis of integral respiration mechanics has revealed a reduction in dynamic lung compliance and an increase in total non-elastic lung resistance during expiration (TNRexp) in HP vs. VP. At the same time, despite the increase in TNRexp in HP, the total work of breathing did not increase. Unlike healthy individuals, the COPD patients were characterized by the absence of differences in regional mechanical properties in both VP and HP. There were no differences in the respiration mechanics of the left lung, and the zones of the right lung only differed in the parameters of regional non-elastic work of breathing (NWBr ) that was increasing from top downwards: the indicators of NWBr during expiration and NWBr in the lower zone were higher as opposed to those of the upper zone in VP. As for HP, NWBr during inspiration, NWBr during expiration and NWBr were higher.Conclusion. The data obtained contradict the prevailing opinion about an escalation in regional differences in ventilation and respiration mechanics under the influence of emerging focal and diffuse inflammatorysclerotic pathological changes in lungs and emphysema.https://bulletin.ssmu.ru/jour/article/view/2397хроническая обструктивная болезнь легкихрегионарная механика дыханияинтегральная механика дыханиявертикальное положение телагоризонтальное положение тела |
| spellingShingle | Al. Ju. Dish An. Ju. Dish T. S. Ageeva A. L. Karzilov A. V. Teteneva T. P. Kalacheva P. E. Mesko E. L. Mishustina A. A. Zaytseva O. S. Paraeva I. D. Bespalova G. E. Chernogoryuk Ventilation and respiration mechanics in patients with chronic obstructive pulmonary disease in different body positions Бюллетень сибирской медицины хроническая обструктивная болезнь легких регионарная механика дыхания интегральная механика дыхания вертикальное положение тела горизонтальное положение тела |
| title | Ventilation and respiration mechanics in patients with chronic obstructive pulmonary disease in different body positions |
| title_full | Ventilation and respiration mechanics in patients with chronic obstructive pulmonary disease in different body positions |
| title_fullStr | Ventilation and respiration mechanics in patients with chronic obstructive pulmonary disease in different body positions |
| title_full_unstemmed | Ventilation and respiration mechanics in patients with chronic obstructive pulmonary disease in different body positions |
| title_short | Ventilation and respiration mechanics in patients with chronic obstructive pulmonary disease in different body positions |
| title_sort | ventilation and respiration mechanics in patients with chronic obstructive pulmonary disease in different body positions |
| topic | хроническая обструктивная болезнь легких регионарная механика дыхания интегральная механика дыхания вертикальное положение тела горизонтальное положение тела |
| url | https://bulletin.ssmu.ru/jour/article/view/2397 |
| work_keys_str_mv | AT aljudish ventilationandrespirationmechanicsinpatientswithchronicobstructivepulmonarydiseaseindifferentbodypositions AT anjudish ventilationandrespirationmechanicsinpatientswithchronicobstructivepulmonarydiseaseindifferentbodypositions AT tsageeva ventilationandrespirationmechanicsinpatientswithchronicobstructivepulmonarydiseaseindifferentbodypositions AT alkarzilov ventilationandrespirationmechanicsinpatientswithchronicobstructivepulmonarydiseaseindifferentbodypositions AT avteteneva ventilationandrespirationmechanicsinpatientswithchronicobstructivepulmonarydiseaseindifferentbodypositions AT tpkalacheva ventilationandrespirationmechanicsinpatientswithchronicobstructivepulmonarydiseaseindifferentbodypositions AT pemesko ventilationandrespirationmechanicsinpatientswithchronicobstructivepulmonarydiseaseindifferentbodypositions AT elmishustina ventilationandrespirationmechanicsinpatientswithchronicobstructivepulmonarydiseaseindifferentbodypositions AT aazaytseva ventilationandrespirationmechanicsinpatientswithchronicobstructivepulmonarydiseaseindifferentbodypositions AT osparaeva ventilationandrespirationmechanicsinpatientswithchronicobstructivepulmonarydiseaseindifferentbodypositions AT idbespalova ventilationandrespirationmechanicsinpatientswithchronicobstructivepulmonarydiseaseindifferentbodypositions AT gechernogoryuk ventilationandrespirationmechanicsinpatientswithchronicobstructivepulmonarydiseaseindifferentbodypositions |