Enhanced Hsp70 expression protects against acute lung injury by modulating apoptotic pathways.

Enhanced Hsp70 expression protects against acute lung injury by modulating apoptotic pathways.

The Acute respiratory distress syndrome (ARDS) is a highly lethal inflammatory lung disorder. Apoptosis plays a key role in its pathogenesis. We showed that an adenovirus expressing the 70 kDa heat shock protein Hsp70 (AdHSP) protected against sepsis-induced lung injury. In this study we tested the...

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Bibliographic Details
Main Authors: Gabriella Aschkenasy, Zohar Bromberg, Nichelle Raj, Clifford S Deutschman, Yoram G Weiss
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3223157?pdf=render

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