4-Oxatricyclo[5.2.1.0<sup>2,6</sup>]dec-8-ene-3,5-dione Derivatives as NMDA Receptor- and VGCC Blockers with Neuroprotective Potential
The impact of excitotoxicity mediated by <i>N</i>-methyl-D-aspartate (NMDA) receptor overactivation and voltage gated calcium channel (VGCC) depolarization is prominent among the postulated processes involved in the development of neurodegenerative disorders. NGP1-01, a polycyclic amine,...
Main Authors: | Ayodeji O. Egunlusi, Sarel F. Malan, Sylvester I. Omoruyi, Okobi E. Ekpo, Jacques Joubert |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-10-01
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Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/25/19/4552 |
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