Diverse antitumor effects of ascorbic acid on cancer cells and the tumor microenvironment
Ascorbic acid has attracted substantial attention for its potential antitumor effects by acting as an antioxidant in vivo and as a cofactor in diverse enzymatic reactions. However, solid proof of its clinical efficacy against cancer and the mechanism behind its effect have not been established. More...
Main Authors: | Takeru Maekawa, Toru Miyake, Masaji Tani, Shinji Uemoto |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-09-01
|
Series: | Frontiers in Oncology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2022.981547/full |
Similar Items
-
Increasing Superoxide Production and the Labile Iron Pool in Tumor Cells May Sensitize Them to Extracellular Ascorbate
by: Mark Frederick Mccarty, et al.
Published: (2014-09-01) -
Systematic Review of Intravenous Ascorbate in Cancer Clinical Trials
by: Gina Nauman, et al.
Published: (2018-07-01) -
Dendritic cells infected with recombinant adenoviral vector encoding mouse fibroblast activation protein‐α and human livin α exert an antitumor effect against Lewis lung carcinoma in mice
by: Zaiting Ye, et al.
Published: (2023-09-01) -
Cancer-Associated Fibroblasts in the Hypoxic Tumor Microenvironment
by: Iljin Kim, et al.
Published: (2022-07-01) -
2-O-α-D-Glucopyranosyl-l-ascorbic acid as an antitumor agent for infusion therapy
by: Kaori Miura, et al.
Published: (2017-07-01)