Long-Term Hypoparathyroidism and Hypophosphatemia in Dialysis Patients
Background and Objectives . Hypoparathyroidism in patients with functioning kidneys leads to hyperphosphatemia. This article reviews data suggesting that hypoparathyroidism in patients on dialysis leads to hypophosphatemia. Design . Clinical data of the following were reviewed: ( a ) a patient with...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2014-06-01
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| Series: | Journal of Investigative Medicine High Impact Case Reports |
| Online Access: | https://doi.org/10.1177/2324709614527258 |
| _version_ | 1818932109008437248 |
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| author | Linda Shavit MD Meyer Lifschitz MD Itzchak Slotki MD |
| author_facet | Linda Shavit MD Meyer Lifschitz MD Itzchak Slotki MD |
| author_sort | Linda Shavit MD |
| collection | DOAJ |
| description | Background and Objectives . Hypoparathyroidism in patients with functioning kidneys leads to hyperphosphatemia. This article reviews data suggesting that hypoparathyroidism in patients on dialysis leads to hypophosphatemia. Design . Clinical data of the following were reviewed: ( a ) a patient with hypoparathyroidism before and during chronic dialysis; ( b ) patients on dialysis with surgically created hypoparathyroidism; ( c ) dialysis patients being treated with Cinacalcet, a calcium-sensing receptor agonist that lowers parathyroid hormone (PTH) levels; and ( d ) dialysis patients being treated with Velcalcetide, a new calcium-sensing receptor agonist that also lowers PTH. Results . In the patient presented in this study, in patients with surgically created hypoparathyroidism, and those receiving Cinacalcet or Velcalcetide, a fall in PTH was associated with hypophosphatemia or a fall in serum phosphorus. Conclusion . In patients on dialysis, hypoparathyroidism may lead to hypophosphatemia. |
| first_indexed | 2024-12-20T04:27:15Z |
| format | Article |
| id | doaj.art-afe3e4fd4feb4783ab7776f697d349e3 |
| institution | Directory Open Access Journal |
| issn | 2324-7096 |
| language | English |
| last_indexed | 2024-12-20T04:27:15Z |
| publishDate | 2014-06-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of Investigative Medicine High Impact Case Reports |
| spelling | doaj.art-afe3e4fd4feb4783ab7776f697d349e32022-12-21T19:53:29ZengSAGE PublishingJournal of Investigative Medicine High Impact Case Reports2324-70962014-06-01210.1177/232470961452725810.1177_2324709614527258Long-Term Hypoparathyroidism and Hypophosphatemia in Dialysis PatientsLinda Shavit MD0Meyer Lifschitz MD1Itzchak Slotki MD2Shaare Zedek Medical Center, Jerusalem, IsraelUniversity of Texas Health Science Center at San Antonio, TexasShaare Zedek Medical Center, Jerusalem, IsraelBackground and Objectives . Hypoparathyroidism in patients with functioning kidneys leads to hyperphosphatemia. This article reviews data suggesting that hypoparathyroidism in patients on dialysis leads to hypophosphatemia. Design . Clinical data of the following were reviewed: ( a ) a patient with hypoparathyroidism before and during chronic dialysis; ( b ) patients on dialysis with surgically created hypoparathyroidism; ( c ) dialysis patients being treated with Cinacalcet, a calcium-sensing receptor agonist that lowers parathyroid hormone (PTH) levels; and ( d ) dialysis patients being treated with Velcalcetide, a new calcium-sensing receptor agonist that also lowers PTH. Results . In the patient presented in this study, in patients with surgically created hypoparathyroidism, and those receiving Cinacalcet or Velcalcetide, a fall in PTH was associated with hypophosphatemia or a fall in serum phosphorus. Conclusion . In patients on dialysis, hypoparathyroidism may lead to hypophosphatemia.https://doi.org/10.1177/2324709614527258 |
| spellingShingle | Linda Shavit MD Meyer Lifschitz MD Itzchak Slotki MD Long-Term Hypoparathyroidism and Hypophosphatemia in Dialysis Patients Journal of Investigative Medicine High Impact Case Reports |
| title | Long-Term Hypoparathyroidism and Hypophosphatemia in Dialysis Patients |
| title_full | Long-Term Hypoparathyroidism and Hypophosphatemia in Dialysis Patients |
| title_fullStr | Long-Term Hypoparathyroidism and Hypophosphatemia in Dialysis Patients |
| title_full_unstemmed | Long-Term Hypoparathyroidism and Hypophosphatemia in Dialysis Patients |
| title_short | Long-Term Hypoparathyroidism and Hypophosphatemia in Dialysis Patients |
| title_sort | long term hypoparathyroidism and hypophosphatemia in dialysis patients |
| url | https://doi.org/10.1177/2324709614527258 |
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