The stress response gene ATF3 is a direct target of the Wnt/β-catenin pathway and inhibits the invasion and migration of HCT116 human colorectal cancer cells.

The stress response gene ATF3 is a direct target of the Wnt/β-catenin pathway and inhibits the invasion and migration of HCT116 human colorectal cancer cells.

Aberrant Wnt/β-catenin signaling is implicated in tumorigenesis and the progression of human colorectal cancers, and mutations in the components of the Wnt/β-catenin signaling pathway are observed in the majority of patients. Therefore, extensive studies on the Wnt signaling pathway and its target g...

Full description

Bibliographic Details
Main Authors: Makoto Inoue, Yohei Uchida, Makoto Edagawa, Manabu Hirata, Jun Mitamura, Daiki Miyamoto, Kenji Taketani, Shigeki Sekine, Junya Kawauchi, Shigetaka Kitajima
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6028230?pdf=render

Similar Items

Similar Items