Multiple papular lesions in a patient with HIV and/or AIDS and coinfected with hepatitis B virus: Amyloidosis
Introduction: The most common form of systemic amyloidosis is amyloid A induced by a chronic inflammation. In HIV-infected patients, elevated serum amyloid A levels might be associated with chronic inflammation. Patient presentation: A 43-year-old male patient was admitted to hospital with a compla...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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AOSIS
2017-08-01
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| Series: | Southern African Journal of HIV Medicine |
| Subjects: | |
| Online Access: | https://sajhivmed.org.za/index.php/hivmed/article/view/735 |
| _version_ | 1818055995094466560 |
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| author | Hayati Demiraslan Kemal Deniz Mehmet Doganay |
| author_facet | Hayati Demiraslan Kemal Deniz Mehmet Doganay |
| author_sort | Hayati Demiraslan |
| collection | DOAJ |
| description | Introduction: The most common form of systemic amyloidosis is amyloid A induced by a chronic inflammation. In HIV-infected patients, elevated serum amyloid A levels might be associated with chronic inflammation.
Patient presentation: A 43-year-old male patient was admitted to hospital with a complaint of papular lesions around his eyes, existing for four months. The patient is receiving antiretroviral therapy. HIV RNA was undetectable, and the CD4 count was 770 cells/mm3. He suffered from a bladder carcinoma for four years. On examination, periocular, perioral and anogenital papules, papular lesions in the meatus of external auditory canal, and intranasal polyps were observed.
Management: Microscopic examination of the biopsy material taken from the periocular lesion and then from perianal polyps revealed eosinophilic deposition, and stained positively by Congo red. Serum amyloid A level was negative. Antiretroviral therapy was continued.
Conclusion: A rare form of amyloidosis in a patient with HIV and/or AIDS and coinfected with hepatitis B virus (HBV) was presented here with cutaneous and mucosal lesions. |
| first_indexed | 2024-12-10T12:21:48Z |
| format | Article |
| id | doaj.art-afeb7436f8914957b7d969e1ad3ee4e0 |
| institution | Directory Open Access Journal |
| issn | 1608-9693 2078-6751 |
| language | English |
| last_indexed | 2024-12-10T12:21:48Z |
| publishDate | 2017-08-01 |
| publisher | AOSIS |
| record_format | Article |
| series | Southern African Journal of HIV Medicine |
| spelling | doaj.art-afeb7436f8914957b7d969e1ad3ee4e02022-12-22T01:49:03ZengAOSISSouthern African Journal of HIV Medicine1608-96932078-67512017-08-01181e1e310.4102/sajhivmed.v18i1.735560Multiple papular lesions in a patient with HIV and/or AIDS and coinfected with hepatitis B virus: AmyloidosisHayati Demiraslan0Kemal Deniz1Mehmet Doganay2Department of Infectious Diseases and Clinical Microbiology, Erciyes UniversityDepartment of Pathology, Erciyes UniversityDepartment of Infectious Diseases and Clinical Microbiology, Erciyes UniversityIntroduction: The most common form of systemic amyloidosis is amyloid A induced by a chronic inflammation. In HIV-infected patients, elevated serum amyloid A levels might be associated with chronic inflammation. Patient presentation: A 43-year-old male patient was admitted to hospital with a complaint of papular lesions around his eyes, existing for four months. The patient is receiving antiretroviral therapy. HIV RNA was undetectable, and the CD4 count was 770 cells/mm3. He suffered from a bladder carcinoma for four years. On examination, periocular, perioral and anogenital papules, papular lesions in the meatus of external auditory canal, and intranasal polyps were observed. Management: Microscopic examination of the biopsy material taken from the periocular lesion and then from perianal polyps revealed eosinophilic deposition, and stained positively by Congo red. Serum amyloid A level was negative. Antiretroviral therapy was continued. Conclusion: A rare form of amyloidosis in a patient with HIV and/or AIDS and coinfected with hepatitis B virus (HBV) was presented here with cutaneous and mucosal lesions.https://sajhivmed.org.za/index.php/hivmed/article/view/735Periocular papulesHIV/AIDSamyloidosisproteinuria |
| spellingShingle | Hayati Demiraslan Kemal Deniz Mehmet Doganay Multiple papular lesions in a patient with HIV and/or AIDS and coinfected with hepatitis B virus: Amyloidosis Southern African Journal of HIV Medicine Periocular papules HIV/AIDS amyloidosis proteinuria |
| title | Multiple papular lesions in a patient with HIV and/or AIDS and coinfected with hepatitis B virus: Amyloidosis |
| title_full | Multiple papular lesions in a patient with HIV and/or AIDS and coinfected with hepatitis B virus: Amyloidosis |
| title_fullStr | Multiple papular lesions in a patient with HIV and/or AIDS and coinfected with hepatitis B virus: Amyloidosis |
| title_full_unstemmed | Multiple papular lesions in a patient with HIV and/or AIDS and coinfected with hepatitis B virus: Amyloidosis |
| title_short | Multiple papular lesions in a patient with HIV and/or AIDS and coinfected with hepatitis B virus: Amyloidosis |
| title_sort | multiple papular lesions in a patient with hiv and or aids and coinfected with hepatitis b virus amyloidosis |
| topic | Periocular papules HIV/AIDS amyloidosis proteinuria |
| url | https://sajhivmed.org.za/index.php/hivmed/article/view/735 |
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