Metabolomics-Guided Hypothesis Generation for Mechanisms of Intestinal Protection by Live Biotherapeutic Products

Metabolomics-Guided Hypothesis Generation for Mechanisms of Intestinal Protection by Live Biotherapeutic Products

The use of live biotherapeutic products (LBPs), including single strains of beneficial probiotic bacteria or consortiums, is gaining traction as a viable option to treat inflammatory-mediated diseases like inflammatory bowel disease (IBD). However, LBPs’ persistence in the intestine is heterogeneous...

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Bibliographic Details
Main Authors: Jiayu Ye, Lauren A. E. Erland, Sandeep K. Gill, Stephanie L. Bishop, Andrea Verdugo-Meza, Susan J. Murch, Deanna L. Gibson
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Biomolecules
Subjects:
live biotherapeutics
gut–liver–brain axis
inflammatory bowel disease
immunometabolism
Online Access:https://www.mdpi.com/2218-273X/11/5/738

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