Implications of Oxybate Dosing Regimen for Sleep, Sleep Architecture, and Disrupted Nighttime Sleep in Patients with Narcolepsy: A Commentary

Implications of Oxybate Dosing Regimen for Sleep, Sleep Architecture, and Disrupted Nighttime Sleep in Patients with Narcolepsy: A Commentary

Abstract Narcolepsy is associated with disrupted nighttime sleep (DNS). Sodium oxybate (SXB; Xyrem®), administered twice nightly, is indicated for the treatment of cataplexy and excessive daytime sleepiness in patients 7 years or older with narcolepsy. Recently, low-sodium oxybate (LXB, Xywav®; for...

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Bibliographic Details
Main Authors: Russell Rosenberg, Rogelio Braceras, Wayne Macfadden, Shawn Candler, Jed Black, Chad Ruoff
Format: Article
Language:English
Published: Adis, Springer Healthcare 2023-09-01
Series:Neurology and Therapy
Subjects:
Narcolepsy
Sodium oxybate
Low-sodium oxybate
Polysomnography
Disrupted nighttime sleep
Nocturnal
Online Access:https://doi.org/10.1007/s40120-023-00543-z

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