Comparison of Corneal Biomechanical Properties Between the Two Eyes in Unilateral Exfoliation Syndrome Cases

Pur po se: To compare the differences in corneal biomechanical parameters between the eyes of patients with unilateral exfoliation syndrome (ES), bilateral ES and normal subjects. Ma te ri al and Met hod: Thirty patients with unilateral ES (Group A), 32 bilateral ES patients (Group B) and 49 healt...

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Bibliographic Details
Main Authors: Ali Bülent Çankaya, Alpaslan Anayol, Pelin Yılmazbaş
Format: Article
Language:English
Published: Galenos Yayinevi 2012-07-01
Series:Türk Oftalmoloji Dergisi
Subjects:
Online Access:http://www.oftalmoloji.org/article_2172/Comparison-Of-Corneal-Biomechanical-Properties-Between-The-Two-Eyes-In-Unilateral-Exfoliation-Syndrome-Cases
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Summary:Pur po se: To compare the differences in corneal biomechanical parameters between the eyes of patients with unilateral exfoliation syndrome (ES), bilateral ES and normal subjects. Ma te ri al and Met hod: Thirty patients with unilateral ES (Group A), 32 bilateral ES patients (Group B) and 49 healthy subjects (Group C) were included in this cross-sectional, non-interventional study. Corneal hysteresis (CH), corneal resistance factor (CRF), corneal-compensated intraocular pressure (IOPcc) and Goldmann-correlated IOP (IOPg) were measured using Ocular Response Analyzer (ORA). Central corneal thickness (CCT) was measured with an ultrasonic pachymeter. The differences in ORA parameters between the eyes of the study and control group participants were analyzed. Re sults: In unilateral ES patients, the mean CH values for eyes with and without exfoliation material were 8.6±2.1 mm Hg and 9.1±1.7 mm Hg, respectively (p=0.004). On the other hand, the differences in both mean CRF and CCT between the two eyes in unilateral ES cases were not statistically significant (p>0.05 for both comparisons). IOPcc was significantly higher in ES eyes than in non-ES eyes (19.3±2.9 mm Hg vs. 17.1±2.7 mm Hg) (p 0.05 for all comparisons). Dis cus si on: In unilateral ES subjects, CH was found to be significantly lower in the eyes with exfoliation. Further studies are needed to establish the relationships between exfoliation, ocular biomechanics and glaucoma. (Turk J Ophthalmol 2012; 42: 269-73
ISSN:1300-0659
2147-2661