Comparison of Corneal Biomechanical Properties Between the Two Eyes in Unilateral Exfoliation Syndrome Cases
Pur po se: To compare the differences in corneal biomechanical parameters between the eyes of patients with unilateral exfoliation syndrome (ES), bilateral ES and normal subjects. Ma te ri al and Met hod: Thirty patients with unilateral ES (Group A), 32 bilateral ES patients (Group B) and 49 healt...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Galenos Yayinevi
2012-07-01
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Series: | Türk Oftalmoloji Dergisi |
Subjects: | |
Online Access: | http://www.oftalmoloji.org/article_2172/Comparison-Of-Corneal-Biomechanical-Properties-Between-The-Two-Eyes-In-Unilateral-Exfoliation-Syndrome-Cases |
Summary: | Pur po se: To compare the differences in corneal biomechanical parameters between the eyes of patients with unilateral exfoliation
syndrome (ES), bilateral ES and normal subjects.
Ma te ri al and Met hod: Thirty patients with unilateral ES (Group A), 32 bilateral ES patients (Group B) and 49 healthy subjects
(Group C) were included in this cross-sectional, non-interventional study. Corneal hysteresis (CH), corneal resistance factor (CRF),
corneal-compensated intraocular pressure (IOPcc) and Goldmann-correlated IOP (IOPg) were measured using Ocular Response
Analyzer (ORA). Central corneal thickness (CCT) was measured with an ultrasonic pachymeter. The differences in ORA parameters
between the eyes of the study and control group participants were analyzed.
Re sults: In unilateral ES patients, the mean CH values for eyes with and without exfoliation material were 8.6±2.1 mm Hg and
9.1±1.7 mm Hg, respectively (p=0.004). On the other hand, the differences in both mean CRF and CCT between the two eyes in
unilateral ES cases were not statistically significant (p>0.05 for both comparisons). IOPcc was significantly higher in ES eyes than in
non-ES eyes (19.3±2.9 mm Hg vs. 17.1±2.7 mm Hg) (p 0.05 for all comparisons).
Dis cus si on: In unilateral ES subjects, CH was found to be significantly lower in the eyes with exfoliation. Further studies are needed
to establish the relationships between exfoliation, ocular biomechanics and glaucoma. (Turk J Ophthalmol 2012; 42: 269-73 |
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ISSN: | 1300-0659 2147-2661 |