Low-level laser efficiency in reparation of bone defects
Introduction/Objective. Bone resorption is a common problem in dentistry, and bone reparation cannot be easily achieved. Several techniques of bone grafting and the use of low-level laser treatment (LLLT) as a new therapeutic optional recommended for improving bone repair were applied. The aim of th...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Serbian Medical Society
2023-01-01
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| Series: | Srpski Arhiv za Celokupno Lekarstvo |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0370-8179/2023/0370-81792300003O.pdf |
| _version_ | 1811155176418967552 |
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| author | Obradović Radmila Vujović Sanja Desnica Jana Stevanović Momir Stanišić Dragana Ognjanović Irena Mikić Mirko Bijelić Borivoj Šubarić Ljiljana Đorđević Vladan |
| author_facet | Obradović Radmila Vujović Sanja Desnica Jana Stevanović Momir Stanišić Dragana Ognjanović Irena Mikić Mirko Bijelić Borivoj Šubarić Ljiljana Đorđević Vladan |
| author_sort | Obradović Radmila |
| collection | DOAJ |
| description | Introduction/Objective. Bone resorption is a common problem in dentistry, and bone reparation cannot be easily achieved. Several techniques of bone grafting and the use of low-level laser treatment (LLLT) as a new therapeutic optional recommended for improving bone repair were applied. The aim of the study was to investigate the influence of LLLT in bone repair of artificially made bone defects in the rat mandible using histomorphometry. Methods. The research was carried out on 60 female rats. Bone defects were made in the mandible, and animals were divided into two groups, each containing 30 animals. In the study group, the implantation site was submitted to GaAlAs laser irradiation 670 nm, 5 mW, 4 minutes per day for 5 days. The control group had no postoperative treatment. The animals were sacrificed after two, six, and eight weeks post LLLT, and preparations were analysed by histomorphometry, determining bone area fraction, bone area, integral density, mean density, and density variation. Results. Histomorphometric analysis revealed statistically higher values of area fraction, area, and integral density in the study group after two and six weeks. However, no beneficial laser effect was noticed after eight weeks. Conclusion. Low-level lasers have a stimulating effect on reparatory mechanisms in the early regeneration stage of artificially made bone defects in the rat mandible and can be used as a useful helping method in bone treatment. |
| first_indexed | 2024-04-10T04:29:46Z |
| format | Article |
| id | doaj.art-aff2ad418dcc4783be75fb83f16b97ea |
| institution | Directory Open Access Journal |
| issn | 0370-8179 2406-0895 |
| language | English |
| last_indexed | 2024-04-10T04:29:46Z |
| publishDate | 2023-01-01 |
| publisher | Serbian Medical Society |
| record_format | Article |
| series | Srpski Arhiv za Celokupno Lekarstvo |
| spelling | doaj.art-aff2ad418dcc4783be75fb83f16b97ea2023-03-10T08:06:27ZengSerbian Medical SocietySrpski Arhiv za Celokupno Lekarstvo0370-81792406-08952023-01-011511-2212510.2298/SARH220922003O0370-81792300003OLow-level laser efficiency in reparation of bone defectsObradović Radmila0Vujović Sanja1https://orcid.org/0000-0002-0685-1709Desnica Jana2https://orcid.org/0000-0002-6022-735XStevanović Momir3https://orcid.org/0000-0002-4665-4566Stanišić Dragana4https://orcid.org/0000-0001-8341-2374Ognjanović Irena5https://orcid.org/0000-0002-3716-4143Mikić Mirko6https://orcid.org/0000-0002-7836-9997Bijelić Borivoj7Šubarić Ljiljana8https://orcid.org/0000-0001-7025-6624Đorđević Vladan9University of Niš, Faculty of Medicine, Niš, SerbiaUniversity of Kragujevac, Faculty of Medical Sciences, Kragujevac, SerbiaUniversity of Kragujevac, Faculty of Medical Sciences, Kragujevac, SerbiaUniversity of Kragujevac, Faculty of Medical Sciences, Kragujevac, SerbiaUniversity of Kragujevac, Faculty of Medical Sciences, Kragujevac, SerbiaUniversity of Kragujevac, Faculty of Medical Sciences, Kragujevac, SerbiaUniversity of Montenegro, Faculty of Medicine, Podgorica, MontenegroUniversity of Belgrade, School of Dental Medicine, Belgrade, SerbiaUniversity of Priština - Kosovska Mitrovica, Faculty of Medicine, Kosovska Mitrovica, SerbiaUniversity of Travnik, Faculty of Pharmacy and Health, Travnik, Federation of Bosnia and Herzegovina, Bosnia and HerzegovinaIntroduction/Objective. Bone resorption is a common problem in dentistry, and bone reparation cannot be easily achieved. Several techniques of bone grafting and the use of low-level laser treatment (LLLT) as a new therapeutic optional recommended for improving bone repair were applied. The aim of the study was to investigate the influence of LLLT in bone repair of artificially made bone defects in the rat mandible using histomorphometry. Methods. The research was carried out on 60 female rats. Bone defects were made in the mandible, and animals were divided into two groups, each containing 30 animals. In the study group, the implantation site was submitted to GaAlAs laser irradiation 670 nm, 5 mW, 4 minutes per day for 5 days. The control group had no postoperative treatment. The animals were sacrificed after two, six, and eight weeks post LLLT, and preparations were analysed by histomorphometry, determining bone area fraction, bone area, integral density, mean density, and density variation. Results. Histomorphometric analysis revealed statistically higher values of area fraction, area, and integral density in the study group after two and six weeks. However, no beneficial laser effect was noticed after eight weeks. Conclusion. Low-level lasers have a stimulating effect on reparatory mechanisms in the early regeneration stage of artificially made bone defects in the rat mandible and can be used as a useful helping method in bone treatment.http://www.doiserbia.nb.rs/img/doi/0370-8179/2023/0370-81792300003O.pdfbonelow-level laser treatmentosteogenesis |
| spellingShingle | Obradović Radmila Vujović Sanja Desnica Jana Stevanović Momir Stanišić Dragana Ognjanović Irena Mikić Mirko Bijelić Borivoj Šubarić Ljiljana Đorđević Vladan Low-level laser efficiency in reparation of bone defects Srpski Arhiv za Celokupno Lekarstvo bone low-level laser treatment osteogenesis |
| title | Low-level laser efficiency in reparation of bone defects |
| title_full | Low-level laser efficiency in reparation of bone defects |
| title_fullStr | Low-level laser efficiency in reparation of bone defects |
| title_full_unstemmed | Low-level laser efficiency in reparation of bone defects |
| title_short | Low-level laser efficiency in reparation of bone defects |
| title_sort | low level laser efficiency in reparation of bone defects |
| topic | bone low-level laser treatment osteogenesis |
| url | http://www.doiserbia.nb.rs/img/doi/0370-8179/2023/0370-81792300003O.pdf |
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