SORL1 variants and risk of late-onset Alzheimer’s disease

SORL1 variants and risk of late-onset Alzheimer’s disease

A recent study reported significant association of late-onset Alzheimer’s disease (LOAD) with multiple single nucleotide polymorphisms (SNPs) and haplotypes in SORL1, a neuronal sortilin-related receptor protein known to be involved in the trafficking and processing of amyloid precursor protein. Her...

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Bibliographic Details
Main Authors: Yonghong Li, Charles Rowland, Joseph Catanese, John Morris, Simon Lovestone, Michael C. O’Donovan, Alison Goate, Michael Owen, Julie Williams, Andrew Grupe
Format: Article
Language:English
Published: Elsevier 2008-02-01
Series:Neurobiology of Disease
Subjects:
Alzheimer’s disease
Single nucleotide polymorphism
Haplotype
Association study
SORL1
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996107002173

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